NRx Newsletters

Format: 04/2017

October 2016

  • New Interim Research Director at PM
  • UHN EVP Education Honoured
  • Immunotherapy Research Funded
  • UHN Researcher Made RSC Fellow

August 2016

  • Supporting Research Innovation
  • New Research EVP Appointed

July 2016

  • Rehabilitation Researcher Honoured
  • Speech Pathology Research Awards

June 2016

  • Prestigious Fellowships
  • Surgical Innovation Recognized
  • Radiation Research Excellence
  • Lifetime Achievement

May 2016

  • Young Investigator Award
  • Kidney Researcher Honoured

April 2016

  • AACR Honours Cancer Researcher
  • Dr. Husain Named Executive Director
  • Genome Canada Funding
  • Lupus Researcher Honoured

April 2015

  • Genome Canada Funding

March 2016

  • Researcher's Toolbox: Sensing Damage
  • Dementia: Send in the Clowns
  • Neurological Disease: Improving Diagnosis
  • Cancer: More Realistic Research Models
  • Epilepsy: Targeting Regions of the Brain for Therapy
  • Research News: Redefining our Research Enterprise

February 2016

  • Kidney Disease: Not a Moment Too Soon
  • Stroke: Barriers Preventing Recovery
  • Cancer: Sabotaging the Immune System
  • Imaging: Detecting Early Signs of Heart Damage
  • Arthritis and Bone Health: the Anatomy of Disease
  • Immunology: Knowing Yourself Better
  • News: Michener Joins the UHN Family
  • Funding: Cell Therapy Investment Announced

January 2016

  • Cardiac Rehab: Realizing Benefits for Women
  • Spinal Injury: Improving Surgical Outcome
  • Brain Cancer: Answering an Age-Old Question
  • Immune Cells: The Roads that Lead to a Macrophage
  • Pancreatic Cancer: New Model to Personalize Treatments
  • UHN's 2015 Research Report: E=Health

December 2015: Year in Review

November 2015

  • Patient Safety: Identifying Weaknesses in the System
  • Cancer: Hospitalization Discrepancy
  • Imaging: Pursuit of Sharper Contrast
  • Arthritis: Sex Differences Explained
  • Alzheimer Disease: Speaking One's Mind
  • Kidney Disease: New Biomarkers Predict Severity

October 2015

  • Neuroscience: Connectivity Curbs Compulsiveness
  • Cardiology: What Makes a Good Heart?
  • Researcher Toolbox: Mind over Matter
  • Brain Injury: Sad, Sleepless Nights
  • Vision Disorders: Connecting the Dots
  • Cancer: Radiotherapy Gaps Identified

September 2015

  • Preventing Falls: Stepping Up Safety
  • Kidney Disease: Predicting who is at Risk
  • Arthritis: Link to Vascular Disease Mortality
  • Sleep Apnea: Importance of Fluid Buildup
  • Surgery: Seeing Tumours more Accurately
  • Cancer: New Treatment Strategy

August 2015

  • Parkinson: How Deep Brain Stimulation Works
  • Rehab: Automated Coach Helps Overcome Disabilities
  • Heart Disease: Encouraging Growth Promotes Healing
  • Surgery: Negotiating Risk in the Operating Room
  • Lung Transplant: Old and Young Benefit Equally
  • Researcher's Toolbox: Modelling Bile Duct Disorders
  • Funding: Government Supports Stem Cell Research

July 2015

  • Alzheimer's Disease: Robots That Give a Helping Hand
  • Cancer: Discovery of Genes Driving Prostate Cancer
  • Obesity: Better to be Inefficient?
  • Genetic Emphysema: Boosting Protein Slows Damage
  • Heart Disease: the Path to Targeted Therapies
  • Cancer: Understanding Uneven Drug Delivery
  • UHN Inventor of the Year Announced

June 2015

  • Breast Cancer: Improving Current Treatment Plans
  • Infrastructure & Innovation: New Funding from CFI
  • Regenerative Medicine: From Stem Cells to Cartilage
  • Stroke: The Right Place at the Right Time
  • Lung Cancer: When Does Chemotherapy Help
  • Genomics: Genome Canada Supports UHN Projects

May 2015

  • Diabetes: Therapeutics Activate Gut Nervous System
  • Preventing Falls: Get a Grip with Better Footwear
  • Obesity: Immune Cells in Gut Impact Blood Sugar
  • Pain Management: Seeing How the Brain Responds
  • Cancer: Artificial Intelligence and Radiotherapy
  • UHN-Developed Medical Technology Products Unveiled
  • Northern Biologics Strikes a Deal

April 2015

  • Lupus: Blood Molecule a Bad Influence on Immune Cells
  • Cancer: New Biomarker for Acute Myeloid Leukemia
  • Cancer: Bursting the Microbubble
  • Rehab: Targeting Depression and the Fear of Falling
  • Schizophrenia: Genes Impact Treatment Response
  • Parkinson Disease: A Test for Early Detection

March 2015

  • Stroke: Detailed Feedback Speeds up Recovery
  • Cancer: Size Matters for Blood Clots
  • Transplantation: Identifying the Best Donor Lungs
  • Turning Genes On or Off: Bringing Loops into the Fold
  • Cancer: Reducing Aggressive Care with Palliative Care
  • UHN's 2014 Research Report Wins Top Award

February 2015

  • Cancer: Tumours Hijack Antioxidants to Survive
  • Physical Activity: Regular Exercise not Enough
  • Osteoarthritis: Eating Away at the Joint
  • Heart Disease: Harmful Effects of Intense Exercise
  • Heart Failure: Inexpensive Test may Save Lives
  • HPC4Health Brings Cloud Computing to Health Research

January 2015

  • Prostate Cancer: New Genetic Test to Personalize Treatment
  • Heart Disease: Promoting Heart Health in Women
  • Researcher's Toolbox: Powerful Tool Predicts Protein Interactions
  • Dementia: White Matter Matters
  • Parkinson Disease: Networks that Control Memory Decline
  • Cancer: How Low Oxygen Levels Promote Tumour Growth
  • UHN's 2014 Research Report: Medicine Gets Personal

December 2014: Year in Review

November 2014

  • Pancreatic Cancer: Blood Proteins Aid in Diagnosis
  • Cancer: Examining the Toxicity of New Drugs
  • Neuroscience: Regulator of Potassium Channel Function Uncovered
  • Transplantation: A Matter of Life and Death
  • Psoriatic Arthritis: Improving Early Detection
  • Researcher's Toolbox: New Approach Identifies Disease-related Proteins

October 2014

  • Stroke: Weekend at Home Contributes to Recovery
  • Cancer: Fertile Ground for Growth
  • Lupus: New Way to Monitor Symptom Flares
  • Prostate Cancer: Accurately Pinpointing Tumours
  • Metabolism: Tipping the Balance towards Fat Release
  • Funding: Cancer Research and New Stroke Drug

September 2014

  • Cancer: A Novel Approach to Decipher Cause
  • Chemical Biology: A New Tool to Study the Role of SETD7 Protein
  • Sleep Apnea: Passively Measuring Fluid Accumulation with Sound
  • Kidney Disease: New Diagnostic Imaging Tools
  • Neuroscience: Revealing Regeneration Strategies for the Injured Central Nervous System
  • Navigating Canada's Research Facilities

August 2014

  • Cancer: Potential AntiCancer Therapeutic Discovered
  • Obesity and Depression: Two Sides of the Same Coin?
  • HIV: Hormone Linked to Low Birth Weights
  • Cancer: Nanoparticles to Visualize and Treat Tumours
  • Breast Cancer: Choosing Reconstruction with Surgery
  • Motion Sickness: What you Hear Matters

May 2014

  • Psoriatic Arthritis: Inflammation that Stiffens Joints and Arteries
  • Cancer: A Carrier Particle for Image-Guided Drug Delivery
  • Stroke: New Approaches Needed to Help Patients Regain Their Stride
  • Parkinson's Disease: Brain Structures Provide Clues to Cognitive Function
  • Type 2 Diabetes: Nervous System Key to Prevention
  • Facility Spotlight: The Vector Core

April 2014

  • Liver Disease: A Breakthrough for Hepatitis C
  • Diabetes: Key Regulator of Insulin Secretion Identified
  • Autoimmune Disease: Cancer may Trigger Attack on Brain
  • Telehealth: Enabling Self-Management of Chronic Disease in Remote Communities
  • Biology: Figuring Out How Cells Get Bigger
  • Research Facilities Available at UHN

March 2014

  • Malaria: Bad Blood and Collateral Damage
  • Prostate Cancer: The Cost of Survival in Ontario
  • Rehabilitation: Brain Imaging as a Predictor of Physical Fitness
  • Cancer: Cost Effectiveness of Personalized Medicine
  • UHN Welcomes New Director for Research Commercialization
  • UHN's 2013 Research Report Wins Top Award

February 2014

  • Vision Disorders: Brain Provides Clues to Protection in the Eye
  • Rehabilitation: Support Influences Return Home after Brain Injury
  • Radiation Therapy: Modelling Changes in Tumour Geometry
  • Leukaemia: Tracing the Earliest Steps of Disease
  • Cancer: Earlier Palliative Care Benefits Patients
  • Medical Care: Factors that Influence Opioid Use after Major Surgery

January 2014

  • Lung Cancer: Smoking Out the Factors That Prevent Quitting
  • Diabetes: Leptin in Gut Lowers Blood Sugar
  • Cardiac Arrest: Muscle Relaxant Improves Survival
  • Spinal Cord Injury: Improving Treatment with Stem Cells and Bioengineering

December 2013: Year in Review

November 2013

  • The Grand Opening of the Krembil Discovery Tower
  • HIV: A Powerful New Treatment
  • Depression: Mapping the Brain to Guide Treatment
  • Community Driven Cancer Research Project Begins
  • Palliative Care: Specialized Therapy to Help Terminally Ill Cancer Patients Feel Better

October 2013

  • Stem Cells: Uncovering Critical Regulator of Blood Cell Development
  • Cardiovascular Disease: Curing Hearts with Stem Cells
  • Neuroscience: Wandering Away from Pain
  • Neuroscience: Making Waves
  • Obesity: Reducing Glucose Production in the Liver
  • Brain Injury: Staying Active is Key to Recovery

September 2013

  • Cancer: The Root Cause of Multiple Myeloma Relapse
  • Liver Cirrhosis and Infection: Acute Kidney Injury Predicts 30-day Mortality
  • Neurological Disorders: Unarrested Development
  • Parkinson's Disease: Impulsive Behaviour and Dopamine
  • Cancer: Immune Cell Found to Have Anti-tumour Properties
  • Heart Disease: Barriers to Rehabilitation

August 2013

  • Cancer: Why Some Treatments May Fail
  • Stem Cells: New Role for GATA-3 in Self-renewal
  • Diabetes: Pancreatic Islet Cell Balancing Act
  • Rehabilitation: Making Powered Wheelchairs Safer
  • Medical Imaging: Modeling Blood Flow in Tumours
  • Ankylosing Spondylitis: Links with Autoimmunity

July 2013

  • Cancer: Developing Better Prognostics for Mantle-Cell Lymphoma
  • Stem Cells: Using "Biowires" to Grow Mature Heart Cells
  • Neuroscience: Visualizing Emotional Responses during Depression Therapy
  • Neurological Disease: Using Stem Cells to Improve Nerve Function
  • Cancer: Revealing the Function of the BRCA1 Gene in Breast Cancer
  • Osteoarthritis: Studying Recovery Time after Total Joint Replacement Surgery

June 2013

  • Stem Cells: Genome-Wide Study of Genes That Regulate Blood Development
  • Cancer: Side Effects of Experimental Therapy for Colorectal Cancer
  • Vascular Disease: Inflammation Regulation by MicroRNA
  • Epilepsy: Brain Signal Variability Predicts Memory Performance
  • Stroke: Brains from Brawn

May 2013

  • Diabetes: Resistance to Glucagon in the Brain
  • Stem Cells: Regulators of Blood Cell Development
  • Lung Cancer: Analyzing the Predictive Value of KRAS Mutations
  • Biochemistry: Development of the First Viable Experimental Model for Systemic Ceramide Accumulation
  • Psoriatic Arthritis: Preventing Joint Damage with TNFa Inhibitors
  • Stroke: Swallowing and Speech Impairments After Stroke

April 2013

  • Liver Disease: A New Approach in the Treatment of Hepatitis C
  • Urology: Prevention of Prostate Disorder Symptoms
  • Eye Disease: A New Mechanism that Regulates Cell Death in the Retina
  • Parkinson's Disease: Unravelling Crossed Signals
  • Lung Transplantation: Preventing Rejection with Gene Therapy
  • Rehabilitation: Measuring Balance

March 2013

  • Neuroscience: Treating Anorexia with Deep Brain Stimulation
  • Cancer: The Causes of Tumours of the Eye
  • Cancer: Targeting Hypoxia Tolerance for Improved Cancer Therapy
  • Diabetes: Glucagon Response to Fasting and Starvation
  • Rehabilitation: Referral Strategies for Women with Heart Disease

February 2013

  • Obesity: The Role of Intestinal Bacteria in Fatty Liver Disease
  • Leukemia: Stem Cell Transplant Therapy for AML
  • Drug Development: New Directions in the Treatment of Multiple Sclerosis
  • Arthritis: The Challenge of Integrating Physical Activity into Daily Life
  • Stroke: Regaining Balance with Visual Cues

January 2013

  • Respiration: Testing a New Model to Treat Lung Injury
  • Cancer: New Discovery for Tumour Growth
  • Cancer: Refining Treatment of Oropharyngeal Cancer
  • Obesity: Protecting the Heart from a High Fat Diet
  • Cardiology: Effect of Sleep Apnea on Heart Function
  • Genetics: Understanding How Drugs Affect the Entire System

December 2012: Year in Review

November 2012

  • Heart Disease: Treating Patients Diagnosed with Diabetes
  • Cancer: Palliative Care Referral Practices in Oncology
  • Cancer: Novel Imaging and Therapeutic In One Tiny Package
  • Bipolar Disorder: Insulin Improves the Mental Performance of Bipolar Patients
  • Sleep Apnea: Making Waves in the Link to Renal Disease

October 2012

  • Cancer: A Single DNA Nucleotide Difference Regulates Breast Cancer Cell Growth
  • Diabetes: The Role of the Brain in Insulin Resistance
  • Malaria: Blood Type Influences Disease Severity
  • Stroke: An Experimental Model Accurately Predicts the Outcomes of a Therapeutic Stroke Drug
  • Genetics: Protein Levels Associated with Behavioural Impairments
  • Heart Disease: Timing of Depression on Patient Outcomes

September 2012

  • UHN Licenses Cancer Treatment Planning Technology to RaySearch Laboratories
  • Cancer: Characterizing the Effect of Genetic Variants in Neuroendocrine Cancers
  • Osteoporosis: Inaccurate Assessment of Fracture Risk in Ontario's Non-Urban Areas
  • Immunology: Insights into HIV Susceptibility
  • SCRIPDB Partners with NIH PubChem

August 2012

  • Cancer: Molecular Mechanisms of Cellular Polarity
  • Medical Imaging: First Microbubble with Inherent Dual Imaging Properties
  • Leukemia: A New Molecular Target for Therapy
  • Medical Care: How Surgical Culture Affects Error
  • Respiration: New Educational Objectives for Mechanical Ventilation Practice
  • Rehabilitation: Measuring Activity with Brain Computer Interface Systems

July 2012

  • Leukemia: An Experimental Model for AML Provides New Insights
  • Cancer Care: Drug Development and Maintaining Quality of Life
  • Rheumatoid Arthritis: Circulating Non-Immune Cells Promote the Spread of Joint Inflammation
  • Bipolar Disorder: Making Beneficial Therapy More Accessible
  • Exercise: Improving Quality of Life in Patients Undergoing Chemotherapy
  • Computational Neuroscience: The Relationship between Individual Neurons and Population Network Activities in the Hippocampus

June 2012

  • Colon Cancer: Understanding Self Renewal and Resistance
  • Patient Care: A Better Predictor of Heart Failure in Emergency Room Care
  • Prostate Cancer: Seeking Out Genetic Variations that Increase Cancer Risk
  • Pancreatitis: How Alcohol Damages the Pancreas
  • Health Outcomes: Chronic Joint Pain in the Canadian Population
  • Influenza: Identifying Risk of Severe Illness

May 2012

  • Kidney Failure: Fish Oils May Provide Benefits for Hemodialysis Patients
  • Diabetes: Glucose Regulation by the Intestine
  • Autoimmunity: Gender Differences in the Immune System
  • Hypertension: Managing Blood Pressure with Your Smartphone
  • Sleep Apnea: Daytime Alertness may Reveal Heart Health
  • Neurology: Exploring the Regulation of Brain Function

April 2012

  • Cancer: A New Understanding of Immune System Responses
  • Breast Cancer: Gene Signatures for Better Treatments
  • Spinal Cord Injury: Reducing Inflammation with a Smart Material
  • Diabetes: New Insight into Insulin Release
  • Prostate Cancer: Predicting Recurrence using Oxygen Levels
  • Stroke Rehabilitation: Determining Fall Prevention Responses in Stroke Patients

March 2012

  • Stroke: Development of World's Most Advanced Neuroprotective Drug
  • Proteomics: A Novel Method to Identify Stem Cell Types
  • Medical Imaging: Novel Tools for Visualizing Tumours Using Nanotechnology
  • Metabolism: Appetite Control in the Brain
  • Rehabilitation: Psychotherapy Promotes Prolonged Benefits in Patients with Brain Injury
  • UHN Licensed Image Guided Irradiator System Reaches 10th Installation Milestone

February 2012

  • Structural Biology: Looking Into the Mechanics of Calcium Release
  • Development: Imprinting in the Mouse Genome
  • Breast Cancer: Risks and Benefits of Prevention
  • Neurology: Controlling the Growth of Neurons
  • Stroke: Exercise Program for Rehabilitation
  • Cancer: Preventing Tumours in Retinoblastoma

January 2012

  • Ovarian Cancer: Drug Delays Disease Progression
  • Immunity: Regulating the Response to Infection
  • Hormone Therapy: Ontario Failing to Treat Osteoporosis-Related Side Effects
  • Metabolism: How the Gut Controls Glucose Production
  • Immunology: A New Model for Injury Repair in the Eye
  • Social Media: The Role of Twitter in Assessing Scientific Impact

December 2011: Year in Review

November 2011

  • UHN and University of Toronto Launch Techna Institute
  • iDAPT: World Class Innovation at Toronto Rehab
  • Prostate Cancer: Combination Treatment Greatly Improves Survival
  • Cardiology: Sodium Intake Increases Risk of Sleep Apnea
  • UHN Educational Tool Licensed to Edwards Lifesciences
  • Inflammatory Arthritis: Identifying Risk of Disease Progression

October 2011

  • PMH Awarded Third National Cancer Institute Contract
  • Immune Disorders: New Insights into Cell Regulation
  • Immunity: Cell Adhesion in Leukocytes
  • Neurology: Uncovering Factors Associated with the Development of Neurons
  • Clinical Trials: The Impact of Announcements on Company Stock Prices
  • Alzheimer's Disease: Quality of Life Assessed by Family Caregivers

September 2011

  • UHN Medical Imaging Tool Licensed to Vexim SA
  • Cancer: Creating a Blueprint of Protein Modifications
  • Cardiology: Distinguishing the Mechanisms of Heart Contraction
  • Psoriatic Arthritis: The Disease within a Disease
  • Pulmonary Disease: Increasing Physical Activity
  • Nanomedicine: Delivery of Anticancer Drugs
  • Cardiology: Reducing Inflammation in Damaged Cardiac Muscle
  • Stroke Prevention: Assessing the Effects of Surgical Revascularization

August 2011

  • Strategic Planning Needs Your Help
  • Autoimmune Diseases: Explaining the Role of PTPN22 in Immunity
  • Leukemia: Stem Cell Properties Correlate with Disease Outcome
  • Immunity: Identifying the Mechanisms Involved in Inflammation of the Colon
  • Spondyloarthritis: Impact on Social Life
  • Radioisotope Therapy: The Future of Antibody Linked Radiotherapy
  • Osteoporosis: Better Prevention from Future Injury

July 2011

  • UHN's New Office of Research Trainees
  • Stem Cells: Isolation of the Purest Blood Stem Cells
  • Clinical Trials: Assessing the Effects of Unpublished Data
  • Gastroenterology: New Insights into Blood Glucose Regulation
  • Blood: New Directions for Disease Treatment
  • Stroke: Understanding the Short-Term Outcomes for Artery Blockage

June 2011

  • UHN and Toronto Rehabilitation Institute Announce Their Integration
  • Neurology: Stimulation of the Motor Cortex Improves Hand Tremors
  • Leukemia: New Cancer Stem Cell Factor Identified
  • Cardiology: New Role for Protein in Heart Function
  • Myeloma: Antitumour Activity with New Therapeutic Drug
  • Stem Cells: Characterizing Neural Stem Cell Development

May 2011

  • Health Services Research at UHN: Strategic Planning Workshop
  • Prostate Cancer: New Findings on the Effects of Supplements
  • Cancer: A New Mechanism for Resistance to Therapy
  • Leukemia: Helping the Immune System Fight Cancer
  • Parkinson's Disease: Enhancing the Therapeutic Benefits of L-DOPA
  • Neuroscience: Understanding the Effect of Seizures in Stroke Patients
  • Acute Lung Injury: New Insight into Factors Involved in Cell and Tissue Damage

April 2011

  • Lung Transplantation: High-Risk Donor Lungs Can Now Be Safely Used for Transplant
  • Respiratory Disease: Long-Term Study on the Effects of Acute Illness
  • Lung Cancer: Changes in Non-Cancer Cells May Predict Patient Outcome
  • Diabetes: New Guidelines for Treating Diabetic Neuropathy
  • Neurology: Surgical Procedure Reverses Loss of Brain Matter
  • Autoimmune Disease: New Suppressor Gene Discovered in Lupus-Prone Mice

March 2011

  • Cancer: Novel Organic Nanoparticles for Cancer Targeting and Treatment
  • Cardiology: Novel Peptide Helps to Prevent Damage Following Cardiovascular Injury
  • Pancreatic Cancer: Hypoxia Predicts Growth and Metastasis
  • Stroke: Why Sleeping Better is Good for Stroke Patients
  • Intracerebral Hemorrhage: Identifying a Culprit in Brain Injury
  • Arthritis: Examining Workplace Activity Limitations

February 2011

  • Leukemia: Uncovering Genetic Diversity in Propagating Cells
  • HIV Infection:  Promoting the Immune Response to Chronic Viral Infections
  • Regenerative Medicine: Development of Heart Cells from Stem Cells
  • Depression: Deep Brain Stimulation Shows Benefit in 3 and 6 Year Follow-Up Study
  • Parkinson Disease: New Insights into the Role of the Cerebellum in Disease Development
  • Heart Disease: A Novel Mechanism of Electrical Remodeling in Cardiac Hypertrophy and Heart Failure

December 2010: Year in Review

October 2010

  • Cancer: Identifying the Cells that Cause Cancer
  • Lung Cancer: Gene Signature Helps Predict Benefits of Chemotherapy
  • Neuroscience: The Cellular Basis of Neural Impulse Transmission
  • Heart Disease: Preventing Injury Following Transplantation
  • Diabetes: Detecting Sugar Sensing Pathways in the Brain
  • Virology: Developing New Methods to Fight off SARS
  • Parkinson's Disease: Learning the Benefits of Combined Therapy

September 2010

  • Primary Biliary Cirrhosis: Confirming Gene Involvement
  • Leukemia: Timing DNA Repair and Cell Death to Prevent Cancer
  • Alzheimer's Disease: Investigating New Stimulating Treatment Techniques
  • Neurology: Understanding How Perception of Pain Affects Recovery

July 2010

  • Influenza A: Identifying New Cell Populations to Battle Disease
  • Immunity and Disease: Applying Cell Therapy to Combat Infectious Disease
  • Hodgkin Lymphoma: Investigating Heart Disease Risk and Cancer Treatment
  • Lupus: Monitoring Heart Disease Risk in Patients
  • Parkinson's Disease: Understanding the Anatomy of Movement

June 2010

  • ELLICSR Opens its Doors
  • Immune System: Revising the 'Road Map' of Blood Development
  • Malignant Mesothelioma: Identifying New Investigative Tools
  • Cancer: Depression in Patients with Advanced Disease
  • Neurology: Targeting Brain Communication Circuits to Understand Disease

May 2010

  • UHN Captures $30M in New Ministry Funding
  • Breast Cancer: Hormone-Driven Cell Growth
  • Irritable Bowel Syndrome: Brain Landscape Changes and Disrupted Communication
  • Neurology: Determining When to Re-Start Anticoagulation
  • Diabetes: Locating the Brain's 'Sweet Spot'

April 2010

  • Structural biology: Understanding How Cells Anchor
  • Malaria: How Maternal Infection Contributes to Low Birth Weight
  • Lymphoma: Opening the Door to New Research and Treatments
  • Lung Cancer: Economic Analysis of Targeted Therapy
  • Parkinson's Disease: Learning the Long-Term Effects of Deep Brain Stimulation

March 2010

  • Lupus: Investigating Antimalarial Treatments
  • Head and Neck Cancer: Using Global Screens for New Target Identification
  • Lung Injury: Getting to the Bottom of Injury Promotion and Prevention
  • Neurology: Establishing a Circulation and Brain Landscape Relationship

February 2010

  • Leukemia: Elucidating Genetic Areas of Control
  • Heart Failure: Tracking Patients after Discharge
  • Cancer: Understanding Timing and Tumor Development
  • Liver Transplant: Determining When and Why to Apply the Surgical Brakes
  • Regenerative Medicine: Repairing the Injured Spinal Cord
  • Rett Syndrome: Surveying Brain Patterns to Increase Disease Knowledge

January 2010

  • Cancer: Changing Current Understanding of Gene Function
  • Leukemia: New Population of Cells Discovered
  • Cancer Biology: Sensitizing 'Tenacious' Tumour Cells
  • Neurology: Detailing the Memory Process
  • Cardiology: Re-Examining Protective Properties of Beta-Blockers

December 2009: Year in Review

November 2009

  • Lung Transplantation: Gene Therapy Repairs Injured Lungs
  • Head & Neck Cancer: Clarifying Trial Terminology
  • Parkinson's Disease: 'Stimulating' Ways to Prevent Falls
  • Diabetes: Focusing on Early Diabetes Complications
  • Brain Injury: Understanding Factors Contributing to Damage
  • Breast Cancer: Understanding the Relationship between Treatment and Menopause

October 2009

  • Atherosclerosis: Outlining Disease Beginnings
  • Cardiology: Understanding the Benefits of Salt
  • Stroke: Suppressing Brain Cell Death
  • Neurology: Mapping Nerve Changes
  • Oral Cancer: Identifying New Biomarkers of Disease
  • Nasopharyngeal Cancer: Elucidating Disease Proteins

September 2009

  • Lung Cancer: Enhancing the Decision-Making Process
  • Diabetes: New Protein Discovery
  • Neurology: Changing Current Beliefs
  • Cancer: Identifying New Potential Drug Use
  • Malaria: Defining Future Treatment Options
  • Neurology: Preventing Ocular Cell Death

July 2009

  • New CFI Funding Announced
  • AL-amyloidosis: Discovering Treatment Strategies
  • Cardiovascular Disease: Treatment Implications
  • Regenerative Medicine: Defining Growth Requirements
  • Parkinson's Disease: Mapping the Effects of Stimulation

June 2009

  • Primary Biliary Cirrhosis: Grabbing Hold of Genetics
  • Ovarian Cancer: Patupilone Phase I Safety Findings
  • Arthritis: Taking a Closer Look at Gender
  • Lung Transplantation: Dealing with Rejection
  • Esophageal Cancer: Identifying Markers of Disease

May 2009

  • Cancer: Boosting the Body's Immune System
  • Breast Cancer: Assessing Risk Early-On
  • Malaria: Pregnancy and Treatment
  • Noonan Syndrome: Discovering the Mechanics of Disease
  • ADHD: Genetics of Disease
  • Kidney Disease: Identifying Growth Pathways

April 2009

  • Malaria: Biomarker Discovery
  • Liver Cancer: Novel Treatment Strategy
  • Parkinson's Disease: Deciphering Cell Communication
  • Neurology: Imaging the Brain
  • Breast Cancer: Revisiting Treatment Strategies

March 2009

  • Cancer: Using Algorithms to Detect Gene Patterns
  • Lung Cancer: Three-Sided Approach to Treatment
  • Neurology: Exploring the Use of New Research Tool
  • Major Depressive Disorder: Profiling Treatment
  • HIV: Evaluating New Therapy Options

February 2009

  • Cancer: New Technology to Study Structure
  • Regenerative Medicine: Novel Findings for Lung Repair
  • Cardiology: Avoiding Acute Kidney Injury
  • Cancer: The Genetics Behind Chronic Myeloid Leukemia
  • Ankylosing Spondilitis: Discovering Biomarkers of Disease

January 2009

  • Cancer: Illustrating Form and Function
  • Cancer: Outpatient Palliative Care Interventions
  • Parkinson's Disease: Investigating Brain Cell Connections
  • Lupus: Monitoring the Advantages of Methotrexate
  • Thyroid Cancer: Revealing Where Growth Starts
  • Virology: The Mechanisms of Infection

December 2008: Year in Review - UHN Research in 2008

November 2008

  • Directing Heart Cell Development
  • 'Checking' Immune Cell Balance
  • Remodeling the Heart After Injury
  • Surprising New Model for Cancer Cell Aging
  • Psoriatic Arthritis Researchers Tackle Fatigue
  • Weight Management Prediction in Anorexia

October 2008

  • Signal Control in Immunity
  • Thyroid Cancer Cells 'Staying Put'
  • 'Current' Neural Regenerative Medicine
  • Injury Mechanics in Neurology

September 2008

  • Landmark $120M Funding to UHN
  • Cancer Protein and Male Infertility
  • Forecasting Hepatitis with Disease Marker
  • 'Report'ing on the Immune System
  • Indicators of Lung Cancer Therapy Response
  • Eating Behaviors in Diabetic Teen Girls

July 2008

  • Enzyme Deficiency in Malaria
  • Genetic Changes Involved in Colorectal Cancer
  • A New Therapeutic Approach for Hepatitis B
  • Family Involvement in Psoriatic Arthritis
  • How Hospital and Surgeon Volume Affects Prostate Cancer
  • Movement Control Tactics in Parkinson's Disease

June 2008

  • Tuning the 'Engine' of Immune Response
  • The Role of Fat in Diabetes and Cardiology
  • Innovative Cancer Treatment Moves to Phase II
  • Defining Mechanisms of Brain Degeneration

May 2008

  • Regenerative Medicine and Cardiac Cells
  • Three-Way Communication in Diabetes
  • Controlling the Host Response in Malaria
  • Arthritis Medication Raises Caution
  • New Potential for Parkinson's Disease
  • Understanding Growth in Pituitary Cancer
  • Lung Cancer and Immune Cells
  • New Predictors in Prostate Cancer

April 2008

  • Hypertrophy and Cardiac Cells
  • Nomograms for Phase II Clinical Trials
  • Stroke and the Penumbra
  • Decision Aids for Cancer Patients

March 2008

  • Smooth Muscle Cells in Cardiology
  • Revisiting Survival in Prostate Cancer
  • Alzheimer's Disease and DBS
  • Gene Targeting in Rett Syndrome
  • Retinoblastoma and Genomic Instability
  • Disease Management in Lupus
  • Couples Intervention for Cancer

January 2008

  • New Tool for Stem Cells
  • 3D Liver Cancer
  • Lupus Development
  • Profiling Cerebral Malaria
  • IBS and Pain
  • Treating Type II Diabetes

Special Holiday Issue: 2007 Research Breakthroughs

November 2007

  • Optimizing Treatment Decisions in Bladder Cancer
  • Childhood Mood Disorders
  • Myeloma: Drug Screen Points to New Therapy
  • Learning to Control Cancer Growth and Survival Genes
  • Motivations Behind Genetic Testing in Colorectal Cancer

October 2007

  • Building Blocks of Cancer Cells
  • Controlling Lung Cancer Growth
  • How Age can Affect Cardiac Patients
  • Understanding the Mechanics of Memory
  • Type 1 Diabetes and the Immune System: The Link
  • Using Stem Cells for Respiratory Diseases
  • Factors Promoting Osteoporosis

June 2007

  • ALS and Protein Folding
  • Brain Tumour Suppressor Gene
  • Cancer Survivors and Cognitive Impairment
  • Pancreatic Cancer Treatment
  • Cardiovascular Disease and Vitamin C
  • Proteins and the Immune Response
  • Glucose Metabolism and Brain Activity
  • Neural Remodeling

May 2007

  • Mapping Human Leukemia in Mice
  • Influenza A Transmission
  • 'Check'ing Out Cancer
  • Rebuilding Myelin in Spinal Cord Injury
  • Personalizing Cancer Treatment
  • Live Donor Transplants Cut Waiting Times
  • Drug Interactions in Cancer
  • Premier's Summit Awards
  • CFI Awards

April 2007

March 2007

February 2007

January 2007

    • Discovering the Cancer "On Ramp"
    • Understanding Cardiac Repair
    • Screening Hodgkin's Lymphoma Survivors
    • New Cancer Drug Target
    • Paying Attention to Genetics in ADHD
    • The Importance of Day/Night Schedules
    • Nerve Architecture
    • Sleep Apnea Featured
    • A Deeper Look into Movement Disorders
    • Protein Balance in Cancer
    • Focusing on Fatigue
    • Engineering Lung Tissue
    • Controlling Arthritis Activity
    • New Informatics Editor-in-Chief
    • Unraveling Statins
    • Microglia in Brain Trauma and Stroke
    • Cell Communication in the Brain
    • Arresting Tumour Growth
    • Alzheimer's Gene Found
    • Examining Breast Tissue Density and Risk
    • Controlling Fat Levels in Diabetes and Obesity
    • Swallowing Disorder Treatments Assessed
    • Multi-pronged Approach for Treating Brain Injuries
    • Notochord Cells Protect Spinal Discs
    • Thyroid Cancer Metastasis Marker Proposed
    • New SARS Animal Model Tested
    • Potential Improvements for Hepatitis C Treatment

    Special Holiday Issue: 2006 Research Breakthroughs

    Special Issue: Research Day 2006

      • Dr. Peggy Farnham 'ChIP'ping Away at Tumour Identity
      • Dr. Lozano Inventor of the Year
      • Trainees of the Year: Bill Ayach, Peter Stogios, and Dr. Cindy Zadikoff
      • Accolades for Presentation Winners
      • Thanks to the Research Day Team
      • Research Breakthrough: Colon Cancer Rooted in Stem Cells

    November 2006

    • Bone Pain Reduced
    • Testing the Fates of Stem Cells
    • Drug Improves Quality of Life in Lung Cancer
    • Importance of Arthritis Education Reinforced
    • New Potential Anti-cancer Agent Found
    • Genetic Disorders: "Record" Result

    October 2006

    Special Issue: Regenerative Medicine

    • Antibody Attacks AML
    • Spinal Cord Injury Stemmed
    • Fabry Symptoms Foiled
    • Anti-Rejection Drug Defined
    • C-kit Sounds Siren
    • Gene Set Match for Lesioned Livers

    September 2006

    • Dendritic Cells Dominate
    • Repair "Troops" Signalled after Heart Attack
    • 3D Structure of Leukemia Molecule Limned
    • (OD)Case Study: Novel Inhibitors

    June 2006

    • ARDS: Study Shows Long-Term Outcomes for Survivors
    • Blood Vessel Disorders: Molecules Offer New Therapy Target
    • Anorexia Nervosa: Study Suggests Need to Reconsider Treatment
    • Cancer: Anti-Aging Molecule May Help in Cancer Fight
    • Brain Surgery: New Model Predicts Outcomes

    May 2006

    • Transplantation: New Test Will Increase Pool of Donor Lungs
    • Alzheimer's Disease: Finding Offers New Therapeutic Targets
    • Cancer: New UHN Software Finds Partner "Suspects"
    • Better Liver Transplants: Answer's in the Genes

    April 2006

    • Balancing Hope & Knowledge in Cancer Decision-Making
    • Molecule Helps Body Clean Up
    • Electrode Brain Treatment Reduces Seizure Number

    March 2006

    • Gene Bars Rod Development
    • Drug Pressures Tumours
    • New Direction for Repairing Blood Vessels

    February 2006

    • Aching to Sleep
    • Imaging Inner Geometry
    • Knowledge of Immune Molecule Growing
    • Enzymes at the Heart of Structural Changes
    • New Repair [c-]Kit for Heart Disease
    • Infection Target Iron-ically Obvious

    January 2006

    • ADHD Genetic Risk Factor
    • DNA Break-ing News
    • Missing Molecule Stops Signals
    • New Role for MyD-88
    • Defect Found in Lupus-like Syndrome

    November 2005

    • Achievements Displayed at Research Day
    • Dr. Michael Sefton Talks Regenerative Medicine
    • 2005 Inventor of the Year: Dr. Joseph Fisher
    • UHN Research Applauds Abstract & Poster Winners
    • Thanks to the Research Day Team test

    October 2005

    • Telomerases Behaving Badly
    • Behind the (Caspase-)Eight Ball
    • Molecule Required for Immune Cell Survival
    • Molecule First in Line
    • OCD-Related Neurons Pinpointed

    September 2005

    • Molecule Mediates Metastasis
    • Stopping Sleep Symptom Silences Sympathetic Signals
    • Motor Memories: Total Recall

    Summer 2005

    • Drug prolongs lung cancer survival (OCI/PMH)
    • Reducing rejection in transplant (TGHRI/TGH)
    • Killer molecule identified (Krembil/TWH)
    • Dynamic duo in heart disease (OCI/PMH and TGHRI/TGH)

    June 2005

    • Age a Factor in Treatment Decisions (OCI/PMH)
    • New Tools in Pancreatic Cancer Research (OCI/PMH)
    • Understanding Xenograft Rejection (TGHRI/TGH)
    • Deep Brain Stimulation Effect Indirect (Krembil/TWH)

    May 2005

    • Genes predicting hep C treatment response identified (TGHRI/TGH, OCI/PMH, Krembil/TWHI)
    • Gene provides protection against Parkinson disease (Krembil/TWH and AMDI/OCI/PMH)
    • First link between immune and hormonal systems pinpointed at UHN (OCI/PMH)
    • Diabetes finding may lead to new preventive and treatment measures (OCI/PMH and Krembil/TWH)

    April 2005

    • Special Issue: New Division Heads Appointed at OCI

    March 2005

    • Fruit Flies and Cancer Research (AMDI/OCI/PMH and OCI/PMH)
    • New Treatment for Depression (Krembil/TWH)
    • Personalized Cancer Therapy (TGHRI/TGH)

    February 2005

    • Women Respond Better to Lung Cancer Treatment (OCI/PMH)
    • Binge/Purge Behaviours Reduce Anorexia Treatment Success (TGHRI/TGH)
    • Phantom Sensations Probed (Krembil/TWH)

    January 2005

    • Finding Will Lead to Targeted Therapies for Heart Disease and Brain Disorders(OCI/PMH)
    • Risk Factor for Dyslexia Identified (Krembil/TWH)
    • DNA Repair in Prostate Cancer: When Too Much Isn't Enough (OCI/PMH)
    • Study Zeroes in on Predictors of Parkinson Disease Survival (Krembil/TWH)
    • Molecule Critical for Fighting Viral-Induced Heart Disease (TGHRI/TGH)
    • Exercise Eases Symptoms of Musculoskeletal Disease (TGHRI/TGH)

    December 2004

      • Defect a Cause of Parkinson Disease (Krembil/TWH)
      • Successful Treatment for Fabry Disease (OCI/PMH)
      • Anxiety Bad for Heart Patients (TGHRI/TGH)
      • Finding Important for Heart Disease (OCI/PMH)

    November 2004

      • New Treatment for Prostate Cancer (OCI/PMH)
      • Clues to Cause of Autoimmune Disease Uncovered (AMDI/OCI/PMH)
      • A Busy Brain May Overlook Pain (Krembil/TWH)
      • Protein Critical for Genome (OCI/PMH)
      • Clues for Treating Rare Cancer Revealed (TGHRI/TGH)
      • Group Therapy Eases Cancer Fears (TGHRI/TGH)

    October 2004

      • Update: Strategic Planning in Research at UHN

    September 2004

      • Combined Therapy Benefits Breast Cancer (OCI/PMH)
      • Flick the Switch on Disease (OCI/PMH)
      • New Treatment for Huntington's Disease (Krembil/TWH)
      • Regulation of Appetite is Complex (TGHRI/TGH)
      • Molecule Protects Infection Fighting Cells (AMDI/OCI/PMH)

    Summer 2004

      • Protein a Cancer Alert (OCI/PMH)
      • Molecular Complexes Control Brain Function (Krembil/TWH)
      • Heavy Hearts Lifted (TGHRI/TGH) Damaged Clock Proteins
      • OCI/PMH) Stroke Culprit Fingered (Krembil/TWH)
      • Heart Disease Risk Factor Identified (TGHRI/TGH)
      • Chromosome Tips and Cancer (AMDI/OCI/PMH)
      • The Kidney's Role in Heart Failure (TGHRI/TGH)

    June 2004

      • Faulty Genes in Breast Cancer (OCI/PMH)
      • Clue to Child Cancer Found (Krembil/TWH)
      • "Hidden" Cells in Leukemia (TGHRI/TGH)
      • Target for Autoimmune Disease Identified (TGHRI/TGH)
      • Gene Therapy and Hodgkin's Disease (OCI/PMH and TGHRI/TGH)
      • Secrets of Body Clock Revealed (Krembil/TWH)

    April 2004

      • Crohn's Disease Gene Found
      • New Target for Spinal Cord Injury Identified
      • PTEN Implicated in Prostate Cancer
      • Gene Expression—a "Change of Heart"

    March 2004

      • New Hope for Neurological Diseases
      • Immune Cells Can Cause Heart Failure
      • Defective B Cells May Hold Key to Lupus
      • Protein a Possible Target for Cancer Therapy

    February 2004 The Continuum of Research at UHN

      • Biomedical Research Types: The Overview
      • Basic Research : Examples
      • Translational Research : Examples
      • Clinical Research : Examples
    • January 2004
      • Brain Damage Culprit Fingered
      • Measuring Dosage: Photodynamic Therapy
      • New Tool for Understanding Brain Chemistry

    December 2003

      • Long-term Effects of Chemotherapy Studied
      • Protein Fuels Autoimmunity
      • Model Helps Choose Best Care for Heart Disease

    November 2003 Clinical Trials at UHN (Part II of II)

      • Finding the Best Treatment for Heart Failure
      • Patients Use Tools to Understand Cancer
      • Treating Psychotic Depression
      • Attacking the Cause of Lung Disease
      • Testing a New Rapid Treatment for Prostate Cancer
      • Imaging Parkinson's Disease
      • Novel Therapy for Ankylosing Spondylitis

    October 2003 Clinical Trials at UHN (Part I of II)

      • Promising New Breast Cancer Drug Validated
      • Drug Acts as "Trojan Horse"
      • Patients Can Enjoy Comforts of Home
      • New Treatment for Malaria
      • Vitamin K and Osteoporosis

    September 2003

      • New Treatment Strikes at SARS
      • A Healthy Body Weight is Key to Treatment Success
      • Too Much Iron Can be Bad for Your Heart
      • New Role for an Old Molecule

    Summer 2003

      • New SARS Test Tested
      • Personalized Care for Colon Cancer
      • Molecule Critical for Immune Function
      • Protein Involved in Brain Development

    June 2003

      • Development of a "Genetic Smart Bomb"
      • New Clues for Treating Immune Disorders
      • Keeping HIV out of Cells

    May 2003 Update on UHN Research Strategic Planning

      • Platform Executives Announced

    April 2003 Celebrating Creativity and Innovation in Research

      • Vitamin A and Malaria
      • Shedding Light on Breast Cancer Risk
      • Viruses for Benefit
      • Entrepreneurs in Research

    March 2003

      • Gene Therapy and Hepatitis C
      • SARS-Related Lung Disease
      • Ankylosing Spondylitis

    February 2003

      • Healing the Heart with Bone Cells
      • Arthritis in La Belle Province
      • Membrane Proteins

    January 2003

      • Cancer Genes and the Genome
      • New Hope for Transplant Recipients
      • Parkinson's Disease