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Princess Margaret Cancer Institute Techna Institute Toronto General Research Institute Toronto Rehabilitation Institute Toronto Western Research Institute

Princess Margaret Cancer Centre

Techna Institute

Toronto General Research Institute

Toronto Rehab Institute

Toronto Western Research Institute

  • Research foci: cancer— genomics, informatics, molecular biology, clinical trials, signalling pathways, structural biology and biophysics.
  • 376 scientists and clinician-scientists
  • $150M external funding
  • more

  • Headquartered at the Banting Building
  • Research foci: guided therapeutics, informatics and communication technologies, nanotechnology and radiochemistry, photonics, design and engineering for health
  • 50 scientists and clinician-scientists
  • more

  • Located at the Toronto General Hospital
  • Research foci: cardiology, transplantation, immunology and infectious disease
  • 256 scientists and clinician-scientists
  • $74M external funding
  • more

  • Located at Toronto Rehab
  • Research foci: rehabilitation sciences, cardiopulmonary fitness and mobility
  • 118 scientists and clinician-scientists
  • $9M external funding
  • more

  • Located at the Toronto Western Hospital
  • Research foci: Neural and visual sciences, musculoskeletal disease and community and population health
  • 161 scientists and clinician-scientists
  • $37M external funding
  • more

Dr. Kieran Murphy Receives Innovation Award
May 22, 2015

Techna Affiliated Faculty and PM Cancer Centre Clinical Researcher Dr. Kieran Murphy received the 2015 Society of Interventional Radiology Foundation Leaders in Innovation Award. The award is presented to "interventional radiology pioneers" who have created new devices and therapeutics that have advanced the care of those suffering from complex conditions. "Award winners demonstrate a passion for medical breakthroughs that improve patient care," said Dr. Stephen T. Kee, the Chair of the Society's Foundation Board.

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Bursting the Microbubble
May 20, 2015

Image-guided cancer therapies rely on the ability to visualize a malignant tumour so that treatment is applied only at that location. This is achieved by injecting a "contrast agent"—a compound that selectively accumulates in cancerous tissue and can be observed by medical imaging methods.

One of the most highly customizable types of contrast agents is a microbubble. These bubbles are very small (1 to 5 microns in diameter) and consist of a shell and gas core. Although they can be readily detected by ultrasound imaging, microbubbles burst when they are exposed to ultrasound. This makes them unusable for imaging purposes, as they can only help visualize tumours over a short window of time. To address this issue, Techna Core Lead and PM Senior Scientist Dr. Gang Zheng invented microbubbles made of a compound called porphyrin.

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New Biomarker for Leukemia Found
May 18, 2015

Acute myeloid leukemia (AML) is a type of blood cancer, characterized by the rapid growth of immature white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. Unless treated, AML is associated with infection, organ failure, bleeding and death. Despite many advances in understanding how AML develops and progresses, there is still a clear need to identify better predictors of therapy response and outcomes.

A recent study led by PM Cancer Centre Affiliate Scientist Dr. Leonardo Salmena and his team examined the association of INPP4B—an enzyme in an important signalling pathway that contributes to cancer development—with various clinical measures in AML.

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