I am interested in electrical oscillations of the brain - both physiological and pathological. I study such oscillations in humans and rodents, both in vivo and in vitro. I am particularly interested in how these oscillations organize activity in the brain, and how cortical microcircuits support such organized activity. We use electrocorticography, local field potential, multielectrode array, and whole cell recordings techniques. We as well use optogenetic techniques to control specific neuronal populations, as we try to elucidate dynamical mechanisms underlying critical state transition like the transition to seizure. A number of computational techniques are employed to characterize activity at the single cell and population level to gain insight to how cellular activity ultimately results in cortical computations, and derangement like those that occur in epilepsy.
Author Correction: Exploring the alpha desynchronization hypothesis in resting state networks with intracranial electroencephalography and wiring cost estimates.
Sci Rep. 2018 Mar 14;8(1):4787
N Engl J Med. 2018 Jan 03;
Exploring the alpha desynchronization hypothesis in resting state networks with intracranial electroencephalography and wiring cost estimates.
Sci Rep. 2017 Nov 15;7(1):15670
Can Med Educ J. 2017 Jun;8(3):e117-e118
Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:2247-2250
Abstracts and Workshops 7th National Spinal Cord Injury Conference November 9 - 11, 2017 Fallsview Casino Resort Niagara Falls, Ontario, Canada.
J Spinal Cord Med. 2017 Nov;40(6):813-869
Brief activation of GABAergic interneurons initiates the transition to ictal events through post-inhibitory rebound excitation.
Neurobiol Dis. 2017 Oct 09;:
Predictive coding: A contemporary view on the burden of normality and forced normalization in individuals undergoing epilepsy surgery.
Epilepsy Behav. 2017 Aug 23;75:110-113
Different neural routes to autobiographical memory recall in healthy people and individuals with left medial temporal lobe epilepsy.
Neuropsychologia. 2017 Aug 10;:
J Neurosurg. 2017 Jul 07;:1-9
Scientist, Krembil Research Institute (Krembil)
Staff Neurosurgeon, Toronto Western Hospital
Surgical Director, Epilepsy Program, Toronto Western Hospital
Associate Professor, Division of Neurosurgery, Department of Surgery; Associate Professor, Institute of Medical Sciences; Faculty, Institute of Biomaterials and Biomedical Engineering, University of Toronto