Keyvan Karkouti, MSc, MD, FRCPC

Senior Scientist, Toronto General Hospital Research Institute (TGHRI)

Keywords: massive blood loss, blood conservation, clinical outcomes, perioperative blood loss

My research is primarily focused on improving the management and outcomes of patients with excessive perioperative blood loss. Other areas of interest are perioperative blood conservation, benefits and harmful effects of blood products, and identification of physiological indications for blood transfusion.

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: renal endpoints.

Br J Anaesth. 2018 Nov;121(5):1013-1024

McIlroy DR, Bellomo R, Billings FT, Karkouti K, Prowle JR, Shaw AD, Myles PS

Point-of-care viscoelastic hemostatic testing in cardiac surgery patients: a systematic review and meta-analysis.

Can J Anaesth. 2018 Sep 07;:

Lodewyks C, Heinrichs J, Grocott HP, Karkouti K, Romund G, Arora RC, Tangri N, Rabbani R, Abou-Setta A, Zarychanski R

Antithrombotic Therapy Management of Adult and Pediatric Cardiac Surgery Patients.

J Thromb Haemost. 2018 Aug 28;:

Baumann Kreuziger L, Karkouti K, Tweddell J, Massicotte MP

Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial.

BMJ Open. 2018 Apr 20;8(4):e020741

Karkouti K, Callum J, Rao V, Heddle N, Farkouh ME, Crowther MA, Scales DC

Use of prothrombin complex concentrate for management of coagulopathy after cardiac surgery: a propensity score matched comparison to plasma.

Br J Anaesth. 2018 May;120(5):928-934

Fitzgerald J, Lenihan M, Callum J, McCluskey SA, Srinivas C, van Rensburg A, Karkouti K

Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and European Coronary Artery Bypass Grafting Bleeding Severity Grade.

Anesthesiology. 2018 Mar 15;:

Bartoszko J, Wijeysundera DN, Karkouti K, Callum J, Rao V, Crowther M, Grocott HP, Pinto R, Scales DC, Achen B, Brar S, Morrison D, Wong D, Bussières JS, de Waal T, Harle C, de Médicis É, McAdams C, Syed S, Tran D, Waters T, Transfusion Avoidance in...

Pre-operative anaemia, intra-operative hepcidin concentration and acute kidney injury after cardiac surgery: a retrospective observational study.

Anaesthesia. 2018 Mar 12;:

Karkouti K, Yip P, Chan C, Chawla L, Rao V

Can predicting transfusion in cardiac surgery help patients?

Br J Anaesth. 2017 Sep 01;119(3):350-352

Bartoszko J, Karkouti K

In reply: Use of early postoperative serum creatinine elevation to identify acute kidney injury after cardiac surgery.

Can J Anaesth. 2017 Sep 25;:

Karkouti K

Losing sight of the precautionary principle.

Transfusion. 2017 Aug;57(8):1854-1856

Karkouti K