Alterations in metabolism are a key indicator of cancer. My research is focused on identifying potential metabolic markers of disease using high-field Nuclear Magnetic Resonance (NMR) spectroscopy and the development of clinical applications of MR-spectroscopic imaging (MRS/I). Clinically, MRS/I provides a non-invasive means of studying biochemical processes intrinsic to tumor development and response to treatment at an earlier stage than is possible using anatomical MRI. MRS/I may also provide prognostic information to select appropriate treatment; a means with which to evaluate tumor sensitivity and resistance to therapy; and ultimately, a better understanding of the biological mechanisms underlying cancer onset and progression.
Andrei Zhivko Damyanovich, MA, MSc, PhD, MCCPM
Clinician Investigator, Princess Margaret Cancer Centre
Cancer Clinical Research Unit (CCRU), Princess Margaret Cancer Centre
Clinician Investigator, Princess Margaret Cancer Centre
Cancer Clinical Research Unit (CCRU), Princess Margaret Cancer Centre
Medical Physicist, Radiation Medicine Program, Princess Margaret Cancer Centre
Assistant Professor, Department of Radiation Oncology, University of Toronto