My general research program examines the interaction between host immunity and environmental triggers in the development of autoimmune disease. My specific focus uses genomics and proteomics to define the immunopathogenesis of ankylosing spondylitis.
Dr. Inman is a rheumatologist and Senior Scientist, recognized for his expertise in autoimmune diseases, particularly spondyloarthritis (SpA) and ankylosing spondylitis (AS). Based at the University of Toronto and Toronto Western Hospital, he has led extensive research into the genetic, immunologic, and clinical mechanisms driving these inflammatory conditions, which affect the spine, joints, and other organs.
Dr. Inman's research contributions are diverse, encompassing the genetic basis of susceptibility to AS, the identification of immune pathways involved in disease progression, and the development of new biomarkers to assess disease activity and treatment response. His work has led to a better understanding of how genetic and environmental factors interact to trigger and sustain inflammation in these diseases, and he has been instrumental in advancing the field of precision medicine for SpA. Additionally, he has contributed significantly to the development of novel therapeutics aimed at modulating the immune system and reducing chronic inflammation in AS patients.
An advocate for patient-centered care, Dr. Inman has also pioneered approaches for early diagnosis and treatment, aiming to improve quality of life and long-term outcomes for individuals with SpA. His work is widely published and has shaped clinical practice guidelines for managing AS, making him a highly respected leader in rheumatology research and patient care.
- Co-Chair, Center for Immunology to Immunotherapy, University Health Network
- Co-Director, Spondylitis Program, University Health Network
- Co-Director, Schroeder Arthritis Institute, University Health Network
- Deputy Physician in Chief Research, University Health Network
- Professor, Department of Immunology, University of Toronto
- Professor, Institute of Medical Science, University of Toronto