Kazuhiro Yasufuku, MD

Dr. Yasufuku is an Associate Professor of Surgery at the University of Toronto and a Staff Thoracic Surgeon at the prestigious Division of Thoracic Surgery at the Toronto General Hospital with special interest in minimally invasive diagnostics and therapeutics. He is the Director of the Interventional Thoracic Surgery Program at the University Health Network (UHN), which includes the Interventional Thoracic Surgery Animal Operating Room capable of high-end endoscopic development and the state-of-the-art Interventional Thoracic Surgery Suite at the Toronto General Hospital for clinical application of new developments. He is also the clinical lead of Thoracic Surgery within the Guided Therapeutics (GTx) program at UHN. He also leads the Thoracic Robotic Surgery Program at UHN. He is a Scientist at the Latner Thoracic Surgery Research Laboratory, Toronto General Hospital Research Institute, UHN.
Dr. Yasufuku's work includes the development of new technology for early diagnosis and ultra-minimally invasive thoracic surgery, translational research in thoracic image guided therapeutics, nanotechnology-enabled image guided intervention for lung cancer, and molecular profiling of advanced stage lung cancer by minimally invasive procedures.
  • Selected Clinical Research Projects
    • 2015 Mar - present: Principal Investigator. Cone-beam CT Guided Microcoil Localization of Pulmonary Nodules during VATS.
    • 2015 Jan - present: Principal Investigator. Feasibility of Minimally Invasive Thoracoscopic Ultrasound for Localization of Pulmonary Nodules Using Resected Human Lungs.
    • 2014 Feb - present: Principal Investigator. Feasibility of a Novel Minimally Invasive Technique for Localization of Pulmonary Nodules Using Spy Thoracoscope System.
    • 2014 Feb - present: Principal Investigator. In Situ Laser Fenestration of Metallic Stents (MS).
    • 2013 May - present: Principal Investigator. Spectrum Image Analysis of Lymph Nodes During Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Patients with Lung Cancer.
    • 2013 Apr - present: Principal Investigator. Pilot Study Using Combined Virtual 4-D EM Tip-Tracked Devices and Endobronchial Ultrasound in the Diagnosis of Peripheral Pulmonary Nodules.
    • 2013 Feb - present: Principal Investigator. Endobronchial ultrasound-guided transbronchial needle aspiration for lymph node staging in patients with non-small cell lung cancer treated with Stereotactic Body Radiotherapy (SBRT). 
    • 2012 Jun - present: Principal Investigator. A Retrospective Analysis of Diagnostic Approaches to Mediastinal Pathology at the University Health Network.
    • 2012 Jan - present: Principal Investigator. Adjuvant melatonin in the prevention of recurrence and mortality following lung cancer resection (AMPLCaRe): a randomized placebo controlled clinical trial.
    • 2011 Aug - present: Principal Investigator. Feasibility of evaluating gene alteration analysis using samples obtained by EBUS-TBNA in patients with lung cancer.
Support Care Cancer. 2018 Nov 14;:
Hirpara DH, Kidane B, Rogalla P, Cypel M, de Perrot M, Keshavjee S, Pierre A, Waddell T, Yasufuku K, Darling GE
J Thorac Cardiovasc Surg. 2018 Oct 06;:
Wang Y, Yeung JC, Hanna WC, Allison F, Paul NS, Waddell TK, Cypel M, de Perrot ME, Yasufuku K, Keshavjee S, Pierre AF, Darling GE
Ann Thorac Surg. 2018 Oct 11;:
Ujiie H, Ding L, Fan R, Kato T, Lee D, Fujino K, Kinoshita T, Lee CY, Waddell TK, Keshavjee S, Wilson BC, Zheng G, Chen J, Yasufuku K
Ann Thorac Surg. 2018 Oct 05;:
Wada H, Zheng J, Gregor A, Hirohashi K, Hu HP, Patel P, Ujiie H, Kato T, Anayama T, Jaffray DA, Yasufuku K
Int J Oncol. 2018 Nov;53(5):2034-2046
Kato T, Jin CS, Lee D, Ujiie H, Fujino K, Hu HP, Wada H, Wu L, Chen J, Weersink RA, Kanno H, Hatanaka Y, Hatanaka KC, Kaga K, Matsui Y, Matsuno Y, De Perrot M, Wilson BC, Zheng G, Yasufuku K
J Heart Lung Transplant. 2018 Sep 05;:
Hashimoto K, Hoetzenecker K, Yeung JC, Jeagal L, Donahoe L, Pierre A, de Perrot M, Yasufuku K, Waddell TK, Keshavjee S, Cypel M
Ann Thorac Surg. 2018 Aug 15;:
Lee CY, Chan H, Ujiie H, Fujino K, Kinoshita T, Irish JC, Yasufuku K
Lung Cancer. 2018 Sep;123:1-6
Hashimoto K, Daddi N, Giuliani M, Hope A, Le LW, Czarnecka K, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K
Respiration. 2018 Jun 13;:1-8
Inage T, Nakajima T, Itoga S, Ishige T, Fujiwara T, Sakairi Y, Wada H, Suzuki H, Iwata T, Chiyo M, Yoshida S, Matsushita K, Yasufuku K, Yoshino I
J Thorac Dis. 2018 Apr;10(4):2388-2396
Kinoshita T, Ujiie H, Schwock J, Fujino K, McDonald C, Lee CY, Gregor A, Tyan CC, Houston S, Czarnecka-Kujwa K, Asamura H, Yasufuku K



Cross Appointed Faculty, Institute of Biomaterials and Biomedical Engineering, University of Toronto
Director of Endoscopy, University Health Network