https://orcid.org/0000-0001-7374-0390Personalization of radiotherapy through the development of mathematical models of molecular (e.g., water, oxygen, chemotherapy drugs, contrast agents) transport in tumours to bridge the gap between “micro-scale” phenomena—tumour hypoxia, vascular architecture, stromal cell/endothelial cell distributions—and macroscopic-scale imaging (e.g., MRI, CT, PET).