Swallowing is a process that is easily ignored by healthy people because it is done automatically without much thought. However, when an accident or disease interferes with this automatic process, the results can be devastating. People with degenerative diseases, head and neck cancer, and stroke survivors are prone to swallowing disorders (also known as dysphagia). Dysphagia involves two primary concerns: the ability to swallow safely (without food, liquid or saliva entering the airway), and the ability to swallow efficiently (without leaving material behind in the throat). The primary focus of the research in my lab is to develop resources that will help clinicians to identify the specific mechanisms of impairment behind problems with airway protection and bolus clearance in swallowing, thereby informing clinical decision making and treatment planning. The primary tool that we use for this work is videofluoroscopy, a dynamic x-ray of swallowing. We are working to establish and validate reference values for a comprehensive set of measures from videofluoroscopy in healthy swallowing across the healthy adult lifespan. This work has involved establishing a standard videofluoroscopy protocol, standard assessment stimuli (liquids of different consistencies), a standard operating procedure for rating, and training materials for researchers and clinicians who wish to use the method (which we call the ASPEKT Method—Analysis of Swallowing Physiology - Events, Kinematics and Timing). We are now extending this work to characterize the pathophysiology of swallowing in specific etiological groups (Parkinson Disease, Chronic Obstructive Pulmonary Disease, Stroke, Head and Neck Cancer, Amyotrophic Lateral Sclerosis, Oculopharyngeal Muscular Dystrophy) and to measure treatment outcomes.