Antonio P Strafella

Dr. Antonio P. Strafella is a neurologist with expertise in movement disorders and functional brain imaging. His research laboratory at the CAMH-PET Imaging Centre developed a clinical research program in movement disorders and neuroimaging (PET and fMRI) to investigate the pathophysiology of motor, cognitive (e.g., executive dysfunction, etc.) and behavioural symptoms (e.g., pathological gambling, dopamine dysregulation, reward system, visual hallucinations) in Parkinson's disease (PD). His lab also combines molecular PET imaging with brain stimulation (transcranial magentic stimulation, deep brain stimulation) techniques to study functional connectivity and receptor binding in the human brain.

Dr. Strafella's research studies have been funded by several granting agencies including CIHR, CFI, Canada Parkinson's Society, National Parkinson Foundation, Parkinson Disease Foundation, Tourette Syndrome Association, E. J. Safra Foundation, Ontario Gambling Research Centre and Canada Research Chair Program.

Specific Research Projects

  • Reward system and impulse control disorders (i.e., pathological gambling) in PD with dopaminergic PET ligands
  • Executive functions and mild cognitive impairment in PD with dopaminergic PET ligands and fMRI
  • Default network in PD with fMRI and PET
  • Prefrontal-striatal functional connectivity with rTMS and DBS in PD with dopaminergic PET ligands
  • Prefrontal-striatal structural connectivity in PD with DTI
  • Microglial activation in PD with PET tracers
Int Rev Psychiatry. 2017 Dec 05;:1-8
Valli M, Strafella AP
Brain Imaging Behav. 2017 Nov 23;:
Malik S, Jacobs M, Cho SS, Boileau I, Blumberger D, Heilig M, Wilson A, Daskalakis ZJ, Strafella AP, Zangen A, Le Foll B
J Cereb Blood Flow Metab. 2017 Jan 01;:271678X17741395
Knezevic D, Verhoeff NPL, Hafizi S, Strafella AP, Graff-Guerrero A, Rajji T, Pollock BG, Houle S, Rusjan PM, Mizrahi R
Brain. 2017 Oct 05;:
Kim J, Criaud M, Cho SS, Díez-Cirarda M, Mihaescu A, Coakeley S, Ghadery C, Valli M, Jacobs MF, Houle S, Strafella AP
Clin Neurophysiol. 2017 Sep 05;128(11):2125-2139
Hallett M, Di Iorio R, Rossini PM, Park JE, Chen R, Celnik P, Strafella AP, Matsumoto H, Ugawa Y
Brain Struct Funct. 2017 Sep 07;:
Coakeley S, Cho SS, Koshimori Y, Rusjan P, Ghadery C, Kim J, Lang AE, Houle S, Strafella AP
Brain Imaging Behav. 2017 Aug 30;:
Valli M, Mihaescu A, Strafella AP
J Alzheimers Dis. 2017 Aug 16;:
Chung JK, Plitman E, Nakajima S, Caravaggio F, Shinagawa S, Iwata Y, Gerretsen P, Kim J, Takeuchi H, Patel R, Chakravarty MM, Strafella A, Graff-Guerrero A, Alzheimer’s Disease Neuroimaging Initiative
NPJ Parkinsons Dis. 2017;3:22
Coakeley S, Strafella AP
Behav Brain Res. 2017 Jun 21;:
Criaud M, Longcamp M, Anton JL, Nazarian B, Roth M, Sescousse G, Strafella AP, Ballanger B, Boulinguez P



Canada Research Chair in Movement Disorders & Neuroimaging
Professor, Department of Medicine, Division of Neurology, University of Toronto
Associate Professor, Institute of Medical Science, University of Toronto
Senior Scientist, PET-Imaging Centre, Centre for Addiction & Mental Health, Toronto
Adjunct Professor, McGill University, Montreal, Quebec