Dr. Antonio P. Strafella is a neurologist with expertise in movement disorders and functional brain imaging. His research laboratory at the CAMH-PET Imaging Centre developed a clinical research program in movement disorders and neuroimaging (PET and fMRI) to investigate the pathophysiology of motor, cognitive (e.g., executive dysfunction, etc.) and behavioural symptoms (e.g., pathological gambling, dopamine dysregulation, reward system, visual hallucinations) in Parkinson's disease (PD). His lab also combines molecular PET imaging with brain stimulation (transcranial magentic stimulation, deep brain stimulation) techniques to study functional connectivity and receptor binding in the human brain.

Dr. Strafella's research studies have been funded by several granting agencies including CIHR, CFI, Canada Parkinson's Society, National Parkinson Foundation, Parkinson Disease Foundation, Tourette Syndrome Association, E. J. Safra Foundation, Ontario Gambling Research Centre and Canada Research Chair Program.

Specific Research Projects

  • Reward system and impulse control disorders (i.e., pathological gambling) in PD with dopaminergic PET ligands
  • Executive functions and mild cognitive impairment in PD with dopaminergic PET ligands and fMRI
  • Default network in PD with fMRI and PET
  • Prefrontal-striatal functional connectivity with rTMS and DBS in PD with dopaminergic PET ligands
  • Prefrontal-striatal structural connectivity in PD with DTI
  • Microglial activation in PD with PET tracers
Mol Neurobiol. 2019 Aug 05;:
Ghadery C, Koshimori Y, Christopher L, Kim J, Rusjan P, Lang AE, Houle S, Strafella AP
Mov Disord. 2019 Jul;34(7):931-933
Strafella AP
Parkinsonism Relat Disord. 2019 Jul 08;:
Trung J, Hanganu A, Jobert S, Degroot C, Mejia-Constain B, Kibreab M, Bruneau MA, Lafontaine AL, Strafella A, Monchi O
Eur J Nucl Med Mol Imaging. 2019 Jul 11;:
Bischof GN, Ewers M, Franzmeier N, Grothe MJ, Hoenig M, Kocagoncu E, Neitzel J, Rowe JB, Strafella A, Drzezga A, van Eimeren T, MINC faculty
Brain. 2019 Jul 06;:
Fiorenzato E, Strafella AP, Kim J, Schifano R, Weis L, Antonini A, Biundo R
Parkinsonism Relat Disord. 2019 Jun 08;:
Rajalingam R, Breen DP, Chen R, Fox S, Kalia LV, Munhoz RP, Slow E, Strafella AP, Lang AE, Fasano A
Curr Neurol Neurosci Rep. 2019 May 28;19(7):38
Ghadery C, Best LA, Pavese N, Tai YF, Strafella AP
Mol Neurobiol. 2019 May 20;:
Kim J, Ghadery C, Cho SS, Mihaescu A, Christopher L, Valli M, Houle S, Strafella AP
Alzheimers Dement (Amst). 2019 Dec;11:301-309
van Eimeren T, Antonini A, Berg D, Bohnen N, Ceravolo R, Drzezga A, Höglinger GU, Higuchi M, Lehericy S, Lewis S, Monchi O, Nestor P, Ondrus M, Pavese N, Peralta MC, Piccini P, Pineda-Pardo JÁ, Rektorová I, Rodríguez-Oroz M, Rominger A, Seppi K,...
Curr Neurol Neurosci Rep. 2019 Apr 02;19(5):24
Best L, Ghadery C, Pavese N, Tai YF, Strafella AP

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Professor, Department of Medicine, Division of Neurology, University of Toronto
Canada Research Chair in Movement Disorders & Neuroimaging
Chair Research, Division of Neurology, University of Toronto 
Director, Parkinson Canada Board 
Faculty Member,  Institute of Medical Science, University of Toronto
Senior Scientist, Research Imaging Centre, Centre for Addiction & Mental Health, Toronto