Shereen Ezzat, MD, FACP, FRCPC

Our lab studies the mechanisms of cancer development in hormone-producing glands (endocrine tumours) including those arising from the thyroid, pituitary, endocrine pancreas and adrenal glands.

We are interested in the mechanisms leading to the transcriptional and epigenetic regulation of tumour-derived growth and survival signals. Our focus is on members of the fibroblast growth factor (FGF) family of receptor tyrosine kinases which play an important role in sporadic and familial forms of these diseases. Signalling emphasis is on non-classical heterophilic interactions with cell adhesion molecules.
Nat Genet. 2018 Jun 18;:
Alvarez MJ, Subramaniam PS, Tang LH, Grunn A, Aburi M, Rieckhof G, Komissarova EV, Hagan EA, Bodei L, Clemons PA, Dela Cruz FS, Dhall D, Diolaiti D, Fraker DA, Ghavami A, Kaemmerer D, Karan C, Kidd M, Kim KM, Kim HC, Kunju LP, Langel Ü, Li Z, Lee J, Li...
Onco Targets Ther. 2018;11:3179-3184
Duan M, Xing H, Wang K, Niu C, Jiang C, Zhang L, Ezzat S, Zhang L
Onco Targets Ther. 2017;10:5459-5462
Zhang L, Zhang C, Yang Z, He M, Zhang L, Ezzat S, Liang X
J Surg Oncol. 2017 Sep 10;:
Samuel N, Ejaz R, Silver J, Ezzat S, Cusimano RJ, Kim RH
Endocr Pathol. 2017 Jul 17;:
Alshaikh OM, Yoon JY, Chan BA, Krzyzanowska MK, Butany J, Asa SL, Ezzat S
Mol Cell Endocrinol. 2017 Jul 12;:
Asa SL, Ezzat S
Mol Cell Endocrinol. 2017 Jul 12;:
Ezzat S, Cheng S, Asa SL
Endocr Relat Cancer. 2017 Apr;24(4):C5-C8
Asa SL, Casar-Borota O, Chanson P, Delgrange E, Earls P, Ezzat S, Grossman A, Ikeda H, Inoshita N, Karavitaki N, Korbonits M, Laws ER, Lopes MB, Maartens N, McCutcheon IE, Mete O, Nishioka H, Raverot G, Roncaroli F, Saeger W, Syro LV, Vasiljevic A,...
Endocr Relat Cancer. 2017 Jan 25;:
Asa SL, Kucharczyk W, Ezzat S



Endocrine Oncology Site Group Head, Toronto General Hospital​
Professor, Medicine and Oncology, University of Toronto​