I conduct research in human volunteers, investigating mechanisms of cardiovascular regulation in health and disease, using methods such as sympathetic nerve recordings, quantitation of heart rate variability, and evaluation of blood flow at rest and during exercise.
John Floras is Professor of Medicine at the University of Toronto. From 1995 to 1999 he was the Head of the Division of Cardiology at Mount Sinai Hospital. From 2004 to 2018, he held the Tier 1 Canada Research Chair in Integrative Cardiovascular Biology. In 1985, at the Toronto General Hospital, he established the first human microneurographic-cardiovascular laboratory in Canada. Since, he has investigated human circulatory and cardiac control mechanisms in human health and disease, with particular emphasis on the role of the autonomic nervous system, cardiovascular peptides, and sleep-related breathing disorders in heart failure. He served as Vice-Chair of the multinational CANPAP and ADVENT-HF trials, evaluating the cardiovascular benefits of treating sleep apnea when present in heart failure and co-edited both editions of ‘Sleep Apnea: Implications for Cardiovascular and Cerebrovascular Disease’ the first text devoted to this topic. His research discoveries appear in more than 300 original contributions. He is past President of the Canadian Hypertension Society and past Chair of the Board of the Banting Research Foundation, Canada’s oldest medical research grant agency.
- Professor, Department of Medicine, University of Toronto
- Senior Clinician Scientist, Lunenfeld-Tanenbaum Research Institute