Lozano Laboratory
We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.

• Lozano AM, Mayberg H, Giacobbe P, Hamani C, Craddock C, Kennedy SH. Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression. Biol Psychiatry 2008 Sep 15;64(6):461-7. Epub 2008 Jul 18.

• Hamani C, McAndrews MP, Cohn M, Oh M, Zumsteg D, Shapiro CM, Wennberg RA, Lozano AM. Memory enhancement induced by hypothalamic/fornix deep brain stimulation. Ann Neurol. 2008 Jan;63(1):119-23.

• Toda H, Hamani C, Fawcett AP, Hutchison WD, Lozano AM. The regulation of adult rodent hippocampal neurogenesis by deep brain stimulation. J Neurosurg. 2008 Jan; 108(1):132-8.

• Lozano AM, Kalia S. New movement in Parkinson's. Scientific American 2005 July 293; (1):68-75.

• Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, Schwalb JM and Kennedy SH. Deep Brain Stimulation for Treatment-Resistant Depression. Neuron 2005 45:651-660.

• Kalia SK, Lee S, Liu L, Crocker SJ, Thorhildur ET, Smith PD, Glover JR, Fon EA, Park DS, Lozano AM. BAG5 Inhibits Parkin and enhances dopaminergic neuron degeneration. Neuron 2004 44(6):931-945.