We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
Ann Clin Transl Neurol. 2019 Jan;6(1):174-185
Mov Disord. 2019 Jan 11;:
Magnetic Resonance-Guided Focused Ultrasound : Current Status and Future Perspectives in Thermal Ablation and Blood-Brain Barrier Opening.
J Korean Neurosurg Soc. 2019 Jan;62(1):10-26
Simultaneous Stimulation of the Globus Pallidus Interna and the Nucleus Basalis of Meynert in the Parkinson-Dementia Syndrome.
Dement Geriatr Cogn Disord. 2019 Jan 10;47(1-2):19-28
J Parkinsons Dis. 2018;8(s1):S79-S83
On the (Non-)equivalency of monopolar and bipolar settings for deep brain stimulation fMRI studies of Parkinson's disease patients.
J Magn Reson Imaging. 2018 Dec 15;:
Parkinsonism Relat Disord. 2018 Nov 28;:
Inferior thalamic peduncle deep brain stimulation for treatment-refractory obsessive-compulsive disorder: A phase 1 pilot trial.
Brain Stimul. 2018 Nov 27;:
Focused ultrasound thalamotomy location determines clinical benefits in patients with essential tremor.
Brain. 2018 Nov 17;:
Mov Disord. 2018 Nov 13;:
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto