Robert E W Chen, MA, MSc, MB BCh, MB BChir

Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.

Ann Neurol. 2015 Feb;77(2):269-80
Christopher L, Duff-Canning S, Koshimori Y, Segura B, Boileau I, Chen R, Lang AE, Houle S, Rusjan P, Strafella AP
Int J Psychophysiol. 2014 Dec;94(3):399-406
Gao X, Cao H, Ming D, Qi H, Wang X, Wang X, Chen R, Zhou P
Neurobiol Aging. 2015 Jan;36(1):301-3
Ni Z, Isayama R, Castillo G, Gunraj C, Saha U, Chen R
Cereb Cortex. 2016 Jan;26(1):58-69
Cash RF, Murakami T, Chen R, Thickbroom GW, Ziemann U
J Neurosci. 2014 May 21;34(21):7314-21
Ni Z, Gunraj C, Kailey P, Cash RF, Chen R
Clin Neurophysiol. 2014 Nov;125(11):2146
Udupa K, Chen R
Science. 2014 Jan 10;343(6167):137
Chen R
Exp Brain Res. 2014 Mar;232(3):1013-23
Kashigar A, Udupa K, Fish J, Chen R
J Neurophysiol. 2014 Mar;111(6):1350-61
Udupa K, Ni Z, Gunraj C, Chen R



Professor, Division of Neurology, Department of Medicine, University of Toronto