Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.
 

Geriatr Orthop Surg Rehabil. 2019;10:2151459318821461
Ikpeze TC, Brodell JD, Chen RE, Oh I
Neurology. 2019 Feb 05;92(6):304
Tipton PW, van Gerpen JA, Chen R
Neurology. 2019 Feb 05;92(6):302-303
Tipton PW, van Gerpen JA, Chen R
Int J Cancer. 2019 Jan 30;:
Ren J, Yang W, Su J, Ren X, Fazelzad R, Albert T, Habbous S, Goldstein DP, de Almeida JR, Hansen A, Jang R, Bratman SV, Hope A, Chen R, Wang J, Xu Y, Cheng D, Zhao Y, Xu W, Liu G
Elife. 2018 09 27;7:
Kistler KE, Trcek T, Hurd TR, Chen R, Liang FX, Sall J, Kato M, Lehmann R
J Neurophysiol. 2019 Jan 09;:
Isayama R, Vesia M, Jegatheeswaran G, Elahi B, Gunraj CA, Cardinali L, Farnè A, Chen R
Arthroscopy. 2018 Dec 24;:
Chen RE, Soin SP, El-Shaar R, Awad HA, Maloney MD, Voloshin I
Front Oncol. 2018;8:594
Chen R, Li H, Li Y, Fazli L, Gleave M, Nappi L, Dong X
Mov Disord Clin Pract. 2018 Sep-Oct;5(5):561-563
Burke MJ, Isayama R, Jegatheeswaran G, Gunraj C, Feinstein A, Lang AE, Chen R

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Professor, Division of Neurology, Department of Medicine, University of Toronto