Robert E W Chen, MA, MSc, MB BCh, MB BChir

Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.
 

Clin Neurophysiol. 2017 Jun;128(6):1109-1115
Phielipp NM, Saha U, Sankar T, Yugeta A, Chen R
Sci Rep. 2017 Feb 27;7:43629
Radhu N, Dominguez LG, Greenwood TA, Farzan F, Semeralul MO, Richter MA, Kennedy JL, Blumberger DM, Chen R, Fitzgerald PB, Daskalakis ZJ
Nat Neurosci. 2017 Apr;20(4):612-619
Park S, Guo Y, Jia X, Choe HK, Grena B, Kang J, Park J, Lu C, Canales A, Chen R, Yim YS, Choi GB, Fink Y, Anikeeva P
Neurology. 2016 11 01;87(18):1907-1915
Brys M, Fox MD, Agarwal S, Biagioni M, Dacpano G, Kumar P, Pirraglia E, Chen R, Wu A, Fernandez H, Wagle Shukla A, Lou JS, Gray Z, Simon DK, Di Rocco A, Pascual-Leone A
CMAJ Open. 2016 Jul-Sep;4(3):E444-E447
Goldenberg NM, Steinberg BE, Rutka JT, Chen R, Cabral V, Rosenblum ND, Kapus A, Lee WL
Sci Rep. 2016 Oct 11;6:34930
Talakoub O, Neagu B, Udupa K, Tsang E, Chen R, Popovic MR, Wong W
Neurology. 2016 Sep 13;87(11):1187-8
van Gerpen JA, Ahlskog JE, Chen R, Fung VS, Hallett M, Gövert F, Deuschl G, Leypoldt F
Schizophr Res. 2016 12;178(1-3):50-55
Bridgman AC, Barr MS, Goodman MS, Zomorrodi R, Rajji T, Le Foll B, Chen R, Daskalakis ZJ, George TP
Mov Disord. 2016 Dec;31(12):1846-1853
Wessel JR, Ghahremani A, Udupa K, Saha U, Kalia SK, Hodaie M, Lozano AM, Aron AR, Chen R

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Professor, Division of Neurology, Department of Medicine, University of Toronto