Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.

Reprod Sci. 2018 Jan;25(1):44-50
Li Y, Li H, Xie N, Chen R, Lee AR, Slater D, Lye S, Dong X
Exp Brain Res. 2018 Jul 21;:
McGregor HR, Vesia M, Rinchon C, Chen R, Gribble PL
Cell Rep. 2017 Dec 05;21(10):2992-3002
Joyce MG, Georgiev IS, Yang Y, Druz A, Geng H, Chuang GY, Kwon YD, Pancera M, Rawi R, Sastry M, Stewart-Jones GBE, Zheng A, Zhou T, Choe M, Van Galen JG, Chen RE, Lees CR, Narpala S, Chambers M, Tsybovsky Y, Baxa U, McDermott AB, Mascola JR, Kwong PD
Reg Anesth Pain Med. 2018 Jul;43(5):559-561
Yoon JW, Richter K, Vivas-Buitrago T, Kim EJ, Chen RE, Quinones-Hinojosa A, Diaz-Gomez JL, Clendenen SR
Int J Med Robot. 2017 Sep;13(3):
Yoon JW, Chen RE, Han PK, Si P, Freeman WD, Pirris SM
Neuroimage. 2017 Sep;158:48-57
Rastogi A, Cash R, Dunlop K, Vesia M, Kucyi A, Ghahremani A, Downar J, Chen J, Chen R
Arch Phys Med Rehabil. 2018 May 24;:
Boulias C, Ismail F, Phadke CP, Bagg S, Bureau I, Charest S, Chen R, Cheng A, Ethans K, Fink M, Finlayson H, Gulasingam S, Guo M, Haziza M, Hosseini H, Khan O, Lang M, Lapp T, Leckey R, Li Pi Shan R, Liem N, Lo A, Mason M, McNeil S, McVeigh S, Miller T...
Parkinsonism Relat Disord. 2018 May 07;:
Nelson AJ, Hoque T, Gunraj C, Chen R
Orthop J Sports Med. 2018 May;6(5):2325967118771286
Chen RE, Papuga MO, Voloshin I, Nicandri GT, Goldblatt JP, Bronstein RD, Rouse LM, Maloney MD



Professor, Division of Neurology, Department of Medicine, University of Toronto