Robert E W Chen, MA, MSc, MB BCh, MB BChir

Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.
 

Brain Stimul. 2011 Jul;4(3):137-44
Rajji TK, Liu SK, Frantseva MV, Mulsant BH, Thoma J, Chen R, Fitzgerald PB, Daskalakis ZJ
J Neurol Neurosurg Psychiatry. 2012 Jan;83(1):91-7
Tsang EW, Hamani C, Moro E, Mazzella F, Lozano AM, Hodaie M, Yeh IJ, Chen R
Brain. 2011 Jul;134(Pt 7):2096-105
Moro E, Schwalb JM, Piboolnurak P, Poon YY, Hamani C, Hung SW, Arenovich T, Lang AE, Chen R, Lozano AM
J Physiol. 2011 Jun 15;589(Pt 12):2955-62
Ni Z, Gunraj C, Wagle-Shukla A, Udupa K, Mazzella F, Lozano AM, Chen R
Cereb Cortex. 2011 Dec;21(12):2863-75
El-Hayek YH, Wu C, Chen R, Al-Sharif AR, Huang S, Patel N, Du C, Ruff CA, Fehlings MG, Carlen PL, Zhang L
Biomaterials. 2011 Jul;32(19):4443-9
Lynch AL, Chen R, Slater NK
Ann Neurol. 2010 Dec;68(6):816-24
Ni Z, Pinto AD, Lang AE, Chen R
J Neurophysiol. 2011 Feb;105(2):749-56
Ni Z, Charab S, Gunraj C, Nelson AJ, Udupa K, Yeh IJ, Chen R
Biol Psychiatry. 2010 Nov 01;68(9):825-31
Voineskos AN, Farzan F, Barr MS, Lobaugh NJ, Mulsant BH, Chen R, Fitzgerald PB, Daskalakis ZJ
Neurology. 2010 Sep 14;75(11):950-9
Tsang EW, Hamani C, Moro E, Mazzella F, Poon YY, Lozano AM, Chen R

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Professor, Division of Neurology, Department of Medicine, University of Toronto