We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
Andres M Lozano
Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature.
Neuroimage. 2015 Oct 23;125:422-427
J Neural Transm. 2015 Oct 6;
Expert Rev Neurother. 2015 Sep 17;:1-10
J Neurol Neurosurg Psychiatry. 2015 Sep 9;
Epilepsia. 2015 Sep 2;
Rapid Modulation of Protein Expression in the Rat Hippocampus Following Deep Brain Stimulation of the Fornix.
Brain Stimul. 2015 Aug 6;
Lancet Psychiatry. 2015 Jul;2(7):585-6
Deep Brain Stimulation Modulates Gamma Oscillations and Theta-Gamma Coupling in Treatment Resistant Depression.
Brain Stimul. 2015 Jun 26;
130 Bilateral Fornix Deep Brain Stimulation for Alzheimer Disease: Surgical Safety in the ADvance Trial.
Neurosurgery. 2015 Aug;62 Suppl 1, CLINICAL NEUROSURGERY:207
Neurology. 2015 Jul 8;
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto