Taufik A Valiante, MD, PhD, FRCSC

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I am interested in electrical oscillations of the brain - both physiological and pathological. I study such oscillations in humans and rodents, both in vivo and in vitro. I am particularly interested in how these oscillations organize activity in the brain, and how cortical microcircuits support such organized activity. We use electrocorticography, local field potential, multielectrode array, and whole cell recordings techniques. We as well use optogenetic techniques to control specific neuronal populations, as we try to elucidate dynamical mechanisms underlying critical state transition like the transition to seizure. A number of computational techniques are employed to characterize activity at the single cell and population level to gain insight to how cellular activity ultimately results in cortical computations, and derangement like those that occur in epilepsy.


Related Links

IEEE Trans Neural Syst Rehabil Eng. 2019 Feb 21;:
Kassiri H, Der Chen F, Salam MT, Chang M, Vatankhahghadim B, Carlen P, Valiante TA, Genov R
J Vis Exp. 2019 Jan 19;(143):
Chang M, Dufour S, Carlen PL, Valiante TA
Front Psychol. 2018;9:1960
White EJ, Nayman C, Dunkley BT, Keller AE, Valiante TA, Pang EW
N Engl J Med. 2018 Jan 03;
Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M, Rauramaa T, Ylä...
Sci Rep. 2017 Nov 15;7(1):15670
Gómez-Ramírez J, Freedman S, Mateos D, Pérez Velázquez JL, Valiante T
Can Med Educ J. 2017 Jun;8(3):e117-e118
Voll S, Valiante TA
Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:2247-2250
O'Leary G, Valiante TA, Genov R
J Spinal Cord Med. 2017 Nov;40(6):813-869
Shojaei MH, Alavinia M, Craven BC, Cheng CL, Plashkes T, Shen T, Fallah N, Humphreys S, O'Connell C, Linassi AG, Ho C, Short C, Ethans K, Charbonneau R, Paquet J, Noonan VK, Furlan JC, Fehlings MG, Craven BC, Likitlersuang J, Sumitro E, Kalsi-Ryan S,...
Neurobiol Dis. 2017 Oct 09;:
Chang M, Dian JA, Dufour S, Wang L, Moradi-Chameh H, Ramani M, Zhang L, Carlen PL, Womelsdorf T, Valiante TA



Staff Neurosurgeon, Toronto Western Hospital
Surgical Director, Epilepsy Program, Toronto Western Hospital
Associate Professor, Division of Neurosurgery, Department of Surgery; Associate Professor, Institute of Medical Sciences; Faculty, Institute of Biomaterials and Biomedical Engineering, University of Toronto