I am interested in electrical oscillations of the brain - both physiological and pathological. I study such oscillations in humans and rodents, both in vivo and in vitro. I am particularly interested in how these oscillations organize activity in the brain, and how cortical microcircuits support such organized activity. We use electrocorticography, local field potential, multielectrode array, and whole cell recordings techniques. We as well use optogenetic techniques to control specific neuronal populations, as we try to elucidate dynamical mechanisms underlying critical state transition like the transition to seizure. A number of computational techniques are employed to characterize activity at the single cell and population level to gain insight to how cellular activity ultimately results in cortical computations, and derangement like those that occur in epilepsy.
Taufik A Valiante
Epilepsy Behav. 2017 May 26;71(Pt A):79-84
Curr Biol. 2017 May 22;27(10):R394-R397
Can J Neurol Sci. 2016 Sep 9;:1-3
Closed-Loop Interruption of Hippocampal Ripples through Fornix Stimulation in the Non-Human Primate.
Brain Stimul. 2016 Aug 2;
Int J Neural Syst. 2016 Jun 6;:1650044
Restoration of Upper Limb Function in an Individual with Cervical Spondylotic Myelopathy using Functional Electrical Stimulation Therapy: A Case Study.
Front Neurol. 2016;7:81
Bridging the Gap between Evidence and Practice for Adults with Medically Refractory Temporal Lobe Epilepsy: Is a Change in Funding Policy Needed to Stimulate a Shift in Practice?
Epilepsy Res Treat. 2015;2015:675071
Inferior-frontal cortex phase synchronizes with the temporal-parietal junction prior to successful change detection.
Neuroimage. 2015 Jun 25;
Theta-gamma coordination between anterior cingulate and prefrontal cortex indexes correct attention shifts.
Proc Natl Acad Sci U S A. 2015 Jun 22;
Scientist, Krembil Research Institute (Krembil)
Staff Neurosurgeon, Toronto Western Hospital
Surgical Director, Epilepsy Program, Toronto Western Hospital
Associate Professor, Division of Neurosurgery, Department of Surgery; Associate Professor, Institute of Medical Sciences; Faculty, Institute of Biomaterials and Biomedical Engineering, University of Toronto