I am interested in electrical oscillations of the brain - both physiological and pathological. I study such oscillations in humans and rodents, both in vivo and in vitro. I am particularly interested in how these oscillations organize activity in the brain, and how cortical microcircuits support such organized activity. We use electrocorticography, local field potential, multielectrode array, and whole cell recordings techniques. We as well use optogenetic techniques to control specific neuronal populations, as we try to elucidate dynamical mechanisms underlying critical state transition like the transition to seizure. A number of computational techniques are employed to characterize activity at the single cell and population level to gain insight to how cellular activity ultimately results in cortical computations, and derangement like those that occur in epilepsy.
Lesion network mapping analysis identifies potential cause of post-operative depression in a case of cingulate low-grade glioma.
World Neurosurg. 2019 Oct 10;:
Severe Intraoperative Orbital Venous Congestion during Resection of a Frontal Meningioma Presenting with Post-operative Vision Loss and Ophthalmoplegia: A Case Report.
Neuroophthalmology. 2019 Aug;43(4):265-268
Arbitrary-Waveform Electro-Optical Intracranial Neurostimulator with Load-Adaptive High-Voltage Compliance.
IEEE Trans Neural Syst Rehabil Eng. 2019 Feb 21;:
J Vis Exp. 2019 Jan 19;(143):
Addressing the Language Binding Problem With Dynamic Functional Connectivity During Meaningful Spoken Language Comprehension.
Front Psychol. 2018;9:1960
Author Correction: Exploring the alpha desynchronization hypothesis in resting state networks with intracranial electroencephalography and wiring cost estimates.
Sci Rep. 2018 Mar 14;8(1):4787
N Engl J Med. 2018 Jan 03;
Exploring the alpha desynchronization hypothesis in resting state networks with intracranial electroencephalography and wiring cost estimates.
Sci Rep. 2017 Nov 15;7(1):15670
Can Med Educ J. 2017 Jun;8(3):e117-e118
Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:2247-2250
Scientist, Krembil Research Institute (Krembil)
Staff Neurosurgeon, Toronto Western Hospital
Surgical Director, Epilepsy Program, Toronto Western Hospital
Associate Professor, Division of Neurosurgery, Department of Surgery; Associate Professor, Institute of Medical Sciences; Faculty, Institute of Biomaterials and Biomedical Engineering, University of Toronto