Sonya MacParland, PhD

The liver is a unique immunological organ and home to cells of the innate and adaptive immune system. Immune dysregulation in the liver is a contributing factor to many disease processes including viral hepatitis, autoimmune hepatitis, liver cancer and inflammatory liver damage leading to fibrosis.

Dr. MacParland's research program is focused on translating fundamental knowledge about the immune biology of the liver into clinical applications. Dr. MacParland and her research team will investigate how liver immune dysregulation drives liver diseases, including chronic viral infection and inflammatory liver fibrosis. They will also examine how the liver immune environment can be therapeutically manipulated using nanoparticles to slow or reverse ongoing damage.

For a list of Dr. MacParland's publications, please visit PubMed or Scopus.


Assistant Professor, Departments of Laboratory Medicine and Pathobiology (LMP) and Immunology, University of Toronto