Robert P Nolan, PhD, CPsych

  • 1. Behavioural Neurocardiac Regulation
    The questions being pursued in my lab focus on how cognitive-emotional functioning influences neuroregulation of heart rate and blood pressure, among individuals with, or at elevated risk for, cardiovascular disease (CVD). This research is interdisciplinary by nature, and it involves collaborations between cardiology, neurology, kinesiology/physiology, medical engineering and psychology. Assessment protocols in our current and planned research focus on neurophysiologic factors associated with vagal-HR control and cardiovagal baroreflex gain, as assessed by EEG, fMRI, heart rate variability, and systolic blood pressure variability. Ultimately, we're interested in how cardiovascular health is affected by symptoms of stress and depression. We're also developing novel behavioural neurocardiac interventions that augment cardioprotective mechanisms, via procedures such as biofeedback, relaxation training and meditation.
     
  • 2. Behavioural Strategies for CVD Risk Factor Reduction
    We are currently completing a 5-year cardiovascular disease (CVD) risk reduction trial in three regions of Ontario known as the Community Outreach Heart Health and Risk Reduction Trial (COHRT). Motivational interviewing in small groups via telephone was used to increase 'readiness to change' lifestyle behaviours (smoking, diet, activity/exercise), among persons at high risk for a primary or secondary cardiovascular event. COHRT also includes sub-studies that are focusing on the interaction between lifestyle, psychological CVD risk factors and neurocardiac regulation. This work represents a collaboration between public health, family medicine, nursing, cardiology and psychology. Future plans are to examine web-based interventions for CVD risk reduction.
     
Circ Cardiovasc Qual Outcomes. 2018 Jul;11(7):e004420
Nolan RP, Feldman R, Dawes M, Kaczorowski J, Lynn H, Barr SI, MacPhail C, Thomas S, Goodman J, Eysenbach G, Liu S, Tanaka R, Surikova J
Can J Cardiol. 2018 Jun;34(6):766-773
Kovacs AH, Grace SL, Kentner AC, Nolan RP, Silversides CK, Irvine MJ
Am J Prev Med. 2018 Feb 15;:
Liu S, Brooks D, Thomas SG, Eysenbach G, Nolan RP
JMIR Mhealth Uhealth. 2016;4(2):e45
Uddin AA, Morita PP, Tallevi K, Armour K, Li J, Nolan RP, Cafazzo JA
Contemp Clin Trials. 2015 Nov 3;
Kovacs AH, Bandyopadhyay M, Grace SL, Kentner AC, Nolan RP, Silversides CK, Jane Irvine M
J Med Internet Res. 2014;16(7):e163
Liu S, Hodgson C, Zbib AM, Payne AY, Nolan RP
Curr Opin Cardiol. 2014 Jul;29(4):319-23
Nolan RP, Liu S, Payne AY
JMIR Res Protoc. 2014;3(1):e5
Nolan RP, Payne AY, Ross H, White M, D'Antono B, Chan S, Barr SI, Gwadry-Sridhar F, Nigam A, Perreault S, Farkouh M, McDonald M, Goodman J, Thomas S, Zieroth S, Isaac D, Oh P, Rajda M, Chen M, Eysenbach G, Liu S, Zbib A

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Assistant Professor, Department of Psychiartry, University of Toronto