Robert Kridel, MD, MPH, PhD

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Dr. Kridel’s lab within the Princess Margaret Cancer Research Tower (MaRS building, East Tower) focuses on translational lymphoma research.
 
Lymphomas arise from the malignant transformation of lymphocytes, a particular type of white blood cells. Collectively, lymphomas represent the 5th most common cause of cancer in Canada, with 10,000 new cases per year. 
 
We have an interest in B-cell lymphomas and are studying scenarios that are associated with poor outcome such as early progression after treatment, transformation to aggressive lymphoma and relapse in the central nervous system. We are applying cutting-edge tools to primary patient samples to unravel tumour heterogeneity and to develop novel, innovative biomarkers to predict outcome in lymphoma. Furthermore, we are leveraging novel findings from discovery platforms to elucidate mechanisms of lymphoma pathogenesis and treatment resistance. Our ultimate goal is to improve patient outcomes through a better understanding of the diversity of responses to treatment and by tailoring therapy to each individual patient.
 

Haematologica. 2018 Mar 15;:
Alig S, Jurinovic V, Pastore A, Bararia D, Häbe S, Hellmuth JC, Kridel R, Gascoyne R, Schmidt C, Zöllner A, Buske C, Dreyling M, Unterhalt M, Hiddemann W, Hoster E, Weigert O
Swiss Med Wkly. 2018 03 08;148:w14596
Steiner R, Kridel R, Giostra E, McKee T, Achermann R, Mueller N, Manuel O, Dickenmann M, Schuurmans MM, de Leval L, Fehr T, Tinguely M, Binet I, Cogliatti S, Haralamvieva E, Koller M, The Swiss Transplant Cohort Study Stcs, Dietrich PY
Blood. 2018 May 03;131(18):2036-2046
Viganò E, Gunawardana J, Mottok A, Van Tol T, Mak K, Chan FC, Chong L, Chavez E, Woolcock B, Takata K, Twa D, Shulha HP, Telenius A, Kutovaya O, Hung SS, Healy S, Ben-Neriah S, Leroy K, Gaulard P, Diepstra A, Kridel R, Savage KJ, Rimsza L, Gascoyne R,...
Best Pract Res Clin Haematol. 2018 Mar;31(1):2-14
Lackraj T, Goswami R, Kridel R
J Mol Diagn. 2018 Mar;20(2):203-214
Hung SS, Meissner B, Chavez EA, Ben-Neriah S, Ennishi D, Jones MR, Shulha HP, Chan FC, Boyle M, Kridel R, Gascoyne RD, Mungall AJ, Marra MA, Scott DW, Connors JM, Steidl C
J Pathol. 2018 Apr;244(5):598-609
Chan FC, Lim E, Kridel R, Steidl C
Blood. 2018 Jan 11;131(2):226-235
Mottok A, Jurinovic V, Farinha P, Rosenwald A, Leich E, Ott G, Horn H, Klapper W, Boesl M, Hiddemann W, Steidl C, Connors JM, Sehn LH, Gascoyne RD, Hoster E, Weigert O, Kridel R
Sci Transl Med. 2017 06 28;9(396):
Oricchio E, Katanayeva N, Donaldson MC, Sungalee S, Pasion JP, Béguelin W, Battistello E, Sanghvi VR, Jiang M, Jiang Y, Teater M, Parmigiani A, Budanov AV, Chan FC, Shah SP, Kridel R, Melnick AM, Ciriello G, Wendel HG
Blood. 2017 07 20;130(3):258-266
Kridel R, Sehn LH, Gascoyne RD
Blood. 2017 05 18;129(20):2760-2770
Ennishi D, Mottok A, Ben-Neriah S, Shulha HP, Farinha P, Chan FC, Meissner B, Boyle M, Hother C, Kridel R, Lai D, Saberi S, Bashashati A, Shah SP, Morin RD, Marra MA, Savage KJ, Sehn LH, Steidl C, Connors JM, Gascoyne RD, Scott DW

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Assistant Professor, Faculty of Medicine, University of Toronto