Dr. Kapoor's research program is directed towards understanding the complex pathophysiology of osteoarthritis (OA) and identifying new therapeutic strategies to counteract the destruction of the articular cartilage during OA. His expertise is in the field of osteoarthritis, cartilage degeneration, fibrosis, biomarkers, autophagy, microRNAs, genetically modified mice, molecular/cellular biology, animal models of disease and OA Tissue Biobank with varying degree of OA disease severity.
His translational research program is directed towards:
- Understanding the complex cellular and molecular mechanisms associated with joint destruction during osteoarthritis
- Identifying reliable biomarkers for early identification of patients with osteoarthritis to enable early intervention using large-scale OA biobank (over 82,000 banked specimens)
- Identifying novel therapeutic targets to stop/delay osteoarthritis and restore joint function
- Understanding key endogenous mechanisms associated with fibrosis during osteoarthritis and connective tissue diseases