Michael F Milosevic, MD, FRCPC

  • Effects of the tumor microenvironment (hypoxia, altered metabolism and high interstitial fluid pressure) on the clinical behavior of human cancers and response to treatment
  • Minimally invasive approaches to evaluating the tumor microenvironment in human cancers using CT, MR, PET or bioluminescence imaging
  • Clinical studies of biologically-targeted treatments to improve the effectiveness of radiotherapy
  • Image-guided adaptive radiotherapy for gynecological cancers
  • Image-guided brachytherapy for gynecological cancers

Clinical Interests
  • Gynecological cancers (Uterine and cervical cancers)
  • Genitourinary cancers (Prostate and bladder cancers)
Radiother Oncol. 2018 Nov 08;:
Welch ML, McIntosh C, Haibe-Kains B, Milosevic MF, Wee L, Dekker A, Huang SH, Purdie TG, O'Sullivan B, Aerts HJWL, Jaffray DA
J Clin Oncol. 2014 Oct 20;32(30_suppl):221
Bass BH, Foxcroft S, Halperin R, McGowan T, Milosevic MF, Parliament M, Warde PR
Lancet Oncol. 2017 May;18(5):e238
Bratman SV, Milosevic MF, Liu FF, Haibe-Kains B
Anticancer Res. 2016 Sep;36(9):4489-92
Smith AD, Truong M, Bristow R, Yip P, Milosevic MF, Joshua AM
Radiother Oncol. 2016 Aug 12;
Han K, Croke J, Foltz W, Metser U, Xie J, Shek T, Driscoll B, Ménard C, Vines D, Coolens C, Simeonov A, Beiki-Ardakani A, Leung E, Levin W, Fyles A, Milosevic MF
Cancer Epidemiol Biomarkers Prev. 2015 Dec 31;
Han K, Pintilie M, Lipscombe LL, Lega IC, Milosevic MF, Fyles AW
Int J Radiat Oncol Biol Phys. 2015 Sep 18;
Milosevic MF, Townsley CA, Chaudary N, Clarke B, Pintilie M, Fan S, Glicksman R, Haider M, Kim S, MacKay H, Yeung I, Hill RP, Fyles A, Oza AM
Semin Radiat Oncol. 2014 Jul;24(3):193-5
Jaffray DA, Carlone MC, Milosevic MF, Breen SL, Stanescu T, Rink A, Alasti H, Simeonov A, Sweitzer MC, Winter JD
Int J Cancer. 2014 Oct 1;135(7):1692-9
Milosevic MF, Pintilie M, Hedley DW, Bristow RG, Wouters BG, Oza AM, Laframboise S, Hill RP, Fyles AW
IEEE Trans Med Imaging. 2012 Jun;31(6):1213-27
Lu C, Chelikani S, Jaffray DA, Milosevic MF, Staib LH, Duncan JS



Professor, Department of Radiation Oncology, University of Toronto