Margaret S Herridge, BSc, MSc, MPH, MD, FRCPC

Senior Scientist, Toronto General Hospital Research Institute (TGHRI)
https://orcid.org/0000-0002-2903-1631
Keywords: quality of life, ICU-acquired weakness, neuropsychological dysfunction, clinical outcomes, critical illness, critical care
Our group is committed to evaluating and improving long-term patient and family caregiver outcomes after critical illness. To date, our research group's interests have included a study on the 5-year outcomes after the acute respiratory distress syndrome (ARDS), one-year outcomes in survivors of the severe acute respiratory syndrome (SARS) and long-stay, ventilated critically ill patients and their family caregivers. We are currently leading a 4-year multi-centre CIHR-funded study "Towards RECOVER" which will evaluate patient and caregiver outcomes to two years after prolonged mechanical ventilation and will help to inform a future family-centered rehabilitation program after severe critical illness.
Canadian Critical Care Society clinical practice guideline: The use of vasopressin and vasopressin analogues in critically ill adults with distributive shock.
Can J Anaesth. 2019 Dec 03;:
Honarmand K, Um KJ, Belley-Côté EP, Alhazzani W, Farley C, Fernando SM, Fiest K, Grey D, Hajdini E, Herridge M, Hrymak C, Møller MH, Kanji S, Lamontagne F, Lauzier F, Mehta S, Paunovic B, Singal R, Tsang JL, Wynne C, Rochwerg B
Correction to: Project management lessons learned from the multicentre CYCLE pilot randomized controlled trial.
Trials. 2019 Oct 25;20(1):606
McCaskell DS, Molloy AJ, Childerhose L, Costigan FA, Reid JC, McCaughan M, Clarke F, Cook DJ, Rudkowski JC, Farley C, Karachi T, Rochwerg B, Newman A, Fox-Robichaud A, Herridge MS, Lo V, Feltracco D, Burns KEA, Porteous R, Seely AJE, Ball IM, Seczek A,...
Fostering community hospital research.
CMAJ. 2019 Sep 03;191(35):E962-E966
Gehrke P, Binnie A, Chan SPT, Cook DJ, Burns KEA, Rewa OG, Herridge M, Tsang JLY
Project management lessons learned from the multicentre CYCLE pilot randomized controlled trial.
Trials. 2019 Aug 28;20(1):532
McCaskell DS, Molloy AJ, Childerhose L, Costigan FA, Reid JC, McCaughan M, Clarke F, Cook DJ, Rudkowski JC, Farley C, Karachi T, Rochwerg B, Newman A, Fox-Robichaud A, Herridge MS, Lo V, Feltracco D, Burns K, Porteous R, Seely AJE, Ball IM, Seczek A,...
From skeletal muscle weakness to functional outcomes following critical illness: a translational biology perspective.
Thorax. 2019 Aug 20;:
Batt J, Herridge MS, Dos Santos CC
Determinants of Depressive Symptoms at 1 Year Following ICU Discharge in Survivors of ≥ 7 Days of Mechanical Ventilation: Results From the RECOVER Program, a Secondary Analysis of a Prospective Multicenter Cohort Study.
Chest. 2019 May 15;:
Hamilton M, Tomlinson G, Chu L, Robles P, Matte A, Burns S, Thomas C, Lamontagne F, Adhikari NKJ, Ferguson N, Friedrich JO, Rudkowski JC, Skrobik Y, Meggison H, Cameron J, Herridge M, RECOVER Program Investigators and the Canadian Critical Care Trials...
Veno-venous extracorporeal life support for blastomycosis-associated acute respiratory distress syndrome.
Perfusion. 2019 Apr 26;:267659119844391
Al-Fares A, Fan E, Husain S, Di Nardo M, Cypel M, Keshavjee S, Herridge MS, Del Sorbo L
Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients.
BMJ Open Respir Res. 2019;6(1):e000383
Kho ME, Molloy AJ, Clarke FJ, Reid JC, Herridge MS, Karachi T, Rochwerg B, Fox-Robichaud AE, Seely AJ, Mathur S, Lo V, Burns KE, Ball IM, Pellizzari JR, Tarride JE, Rudkowski JC, Koo K, Heels-Ansdell D, Cook DJ
Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI.
Clin J Am Soc Nephrol. 2019 Apr 05;14(4):496-505
Bagshaw SM, Adhikari NKJ, Burns KEA, Friedrich JO, Bouchard J, Lamontagne F, McIntrye LA, Cailhier JF, Dodek P, Stelfox HT, Herridge M, Lapinsky S, Muscedere J, Barton J, Griesdale D, Soth M, Ambosta A, Lebovic G, Wald R, Canadian Critical Care Trials...
Acute respiratory distress syndrome.
Nat Rev Dis Primers. 2019 Mar 14;5(1):18
Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS

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Senior Scientist, Toronto General Hospital Research Institute (TGHRI)

Scientist, Division of Experimental Therapeutics - Respiratory & Critical Care, Toronto General Hospital Research Institute (TGHRI)
Clinician Scientist, Co-Principal Investigator, Program in Outcomes and Rehabilitation After Critical Illness
Professor, Department Medicine, University of Toronto