Mamatha Bhat, MD, MSc, FRCPC

Dr. Mamatha Bhat graduated from medical school at McGill University and completed a residency in Internal Medicine and Gastroenterology at the McGill University Health Centre. Next, she completed an MSc in Experimental Medicine, as part of the Royal College Clinician Investigator Program, which was funded by a Resident Physician Health Research Career Training fellowship from the Fonds de Recherche du Quebec – Sante (FRQS). Dr. Bhat also completed a fellowship in Transplant Hepatology at Mayo Clinic in Rochester, Minnesota. She continued her research training at McGill University through a CIHR Fellowship for Health Professionals, during which she studied mRNA translation in hepatocellular carcinoma.

Dr. Bhat is currently a staff Hepatologist and clinician-scientist at UHN's Multi Organ Transplant Program and UofT's Division of Gastroenterology. She is developing a research program to enable precision medicine in hepatocellular carcinoma, non-alcoholic steatohepatitis and liver regeneration in the context of liver transplantation. Dr. Bhat’s research program employs a bench-to-bedside paradigm that connects clinical outcomes with basic research using tools from epidemiology and systems biology, including bioinformatic analysis of ‘omic datasets (e.g., transcriptomic, miRNA, methylation, intestinal microbiome). Her work will contribute to a better understanding of dysregulated gene expression, protein-protein interactions and key pathways that underpin these clinical conditions, as well as the identification of optimal therapeutic targets to treat them. Moreover, she will examine the relationship between ‘omic datasets and clinical outcomes and will validate her findings using patient samples/clinical cohorts, as well as in silico, in vitro and in vivo approaches. Dr. Bhat has assembled a multidisciplinary research team who is conducting projects at the intersection of basic science, informatics and clinical outcomes/epidemiology.
 

Clin Transplant. 2018 Jun 26;:e13304
Goldaracena N, Barbas AS, Galante A, Sapisochin G, Al-Adra D, Selzner N, Galvin Z, Cattral MS, Greig PD, Lilly L, Bhat M, McGilvray ID, Ghanekar A, Levy G, Grant DR, Selzner M
Liver Transpl. 2018 Jun;24(6):779-789
Kollmann D, Sapisochin G, Goldaracena N, Hansen BE, Rajakumar R, Selzner N, Bhat M, McCluskey S, Cattral MS, Greig PD, Lilly L, McGilvray ID, Ghanekar A, Grant DR, Selzner M
Semin Liver Dis. 2018 May;38(2):134-144
Gorgen A, Goldaracena N, Zhang W, Rosales R, Ghanekar A, Lilly L, Cattral M, Greig P, McCluskey S, McGilvray I, Selzner N, Bhat M, Selzner M, Levy G, Grant D, Sapisochin G
World J Hepatol. 2018 Jan 27;10(1):155-165
Bhat V, Srinathan S, Pasini E, Angeli M, Chen E, Baciu C, Bhat M
Transplantation. 2018 Apr;102(4):640-647
Sadler EM, Mehta N, Bhat M, Ghanekar A, Greig PD, Grant DR, Yao F, Sapisochin G
PLoS One. 2017;12(12):e0189223
Baciu C, Pasini E, Angeli M, Schwenger K, Afrin J, Humar A, Fischer S, Patel K, Allard J, Bhat M
Transpl Int. 2017 Nov;30(11):1140-1149
Aravinthan AD, Barbas AS, Doyle AC, Tazari M, Sapisochin G, Cattral MS, Ghanekar A, McGilvray ID, Selzner M, Greig PD, Bhat M, Selzner N, Grant DR, Lilly LB, Renner EL

Pages