Lillian L Siu, MD, FRCPC

Dr. Lillian Siu is a Senior Staff Physician in the Division of Medical Oncology and Hematology at Princess Margaret Hospital since 1998, and is a Professor of Medicine at the University of Toronto. Dr. Siu is Director of the Phase I Program and Co-Director of the Robert and Maggie Bras and Family Drug Development Program at Princess Margaret Hospital.

Dr. Siu is the recipient of national and international awards such as the Elsie Winifred Crann Award from the University of Toronto in 2001 and the Michaele C. Christian Award in Oncology Drug Development from the US National Cancer Institute in 2010. Internationally, Dr. Siu has been a member of the AACR International Membership Committee, the ASCO Head and Neck Cancer Scientific Program Subcommittee and the EORTC Protocol Review Committee. Dr. Siu was the Neuroendocrine Tumor Task Force Chair in the North American Gastrointestinal Intergroup Scientific Steering Committee from 2007-2009, and she was the ASCO Grants Selection Committee Chair in 2009-10. In 2009, Dr. Siu was awarded a Cancer Care Ontario Tier 1 Chair in Experimental Therapeutics. Dr. Siu has a strong background in clinical trial methodology and has been a member of the Program Committees for the ECCO/ASCO/AACR workshop in Flims, Switzerland and the AACR/ASCO workshop in Vail, Colorado. Dr. Siu has published over 110 peer-reviewed manuscripts, and she is currently on the Editorial Boards of Journal of Clinical Oncology, European Journal of Cancer and Cancer Discovery
Developmental Therapeutics and Phase I Clinical Trials of Novel Agents

Dr. Siu's major research focus is in the area of new anticancer drug development, particularly with respect to phase I trials and head and neck malignancies. She is the principal investigator of a phase I cooperative agreement U01 award (2008-2013) sponsored by the United States National Cancer Institute, which aims to expedite the access and evaluation of novel anti-cancer agents.

Related Links

Clin Med Insights Oncol. 2018;12:1179554918779581
Malone E, Siu LL
Int J Radiat Oncol Biol Phys. 2018 May 02;:
Ng WT, Tung SY, Lee V, Ngan RKC, Choi HCW, Chan LLK, Leung TW, Siu LL, Lu TX, Tan T, Tan EH, Sze HCK, Ng AWY, Yiu HHY, O'Sullivan B, Chappell R, Lee AWM
Oncotarget. 2018 Apr 27;9(32):22559-22570
Korpanty GJ, Kamel-Reid S, Pintilie M, Hwang DM, Zer A, Liu G, Leighl NB, Feld R, Siu LL, Bedard PL, Tsao MS, Shepherd FA
J Clin Oncol. 2018 May 07;:JCO2018782292
Lewin J, Soria JC, Stathis A, Delord JP, Peters S, Awada A, Aftimos PG, Bekradda M, Rezai K, Zeng Z, Hussain A, Perez S, Siu LL, Massard C
Head Neck. 2018 Apr 17;:
Bernstein LJ, Pond GR, Gan HK, Tirona K, Chan KK, Hope A, Kim J, Chen EX, Siu LL, Razak ARA
Eur J Cancer. 2018 Apr 06;95:38-51
Iafolla MAJ, Selby H, Warner K, Ohashi PS, Haibe-Kains B, Siu LL
Invest New Drugs. 2018 Apr 03;:
Aghajanian C, Bell-McGuinn KM, Burris HA, Siu LL, Stayner LA, Wheler JJ, Hong DS, Kurkjian C, Pant S, Santiago-Walker A, Gauvin JL, Antal JM, Opalinska JB, Morris SR, Infante JR
Breast Cancer Res Treat. 2017 Nov 24;:
Pezo RC, Chen TW, Berman HK, Mulligan AM, Razak AA, Siu LL, Cescon DW, Amir E, Elser C, Warr DG, Sridhar SS, Yu C, Wang L, Stockley TL, Kamel-Reid S, Bedard PL
JAMA Otolaryngol Head Neck Surg. 2017 Nov 22;:
Zer A, Pond GR, Razak ARA, Tirona K, Gan HK, Chen EX, O'Sullivan B, Waldron J, Goldstein DP, Weinreb I, Hope AJ, Kim JJ, Chan KKW, Chan AK, Siu LL, Bernstein LJ



Professor of Medicine, University of Toronto
Staff Physician, Division of Medical Oncology and Hematology, Princess Margaret Hospital
Director, Phase I Program and Co-Director, Robert and Maggie Bras and Family Drug Development Program, Princess Margaret Hospital