Laura A Dawson, MD, FRCPC

The development of high-precision radiation techniques enables radiation to be investigated as a treatment for tumours previously unsuitable for radiotherapy due to proximity to critical adjacent normal tissues. An example is primary and metastatic liver cancer, a site where local therapy with surgery has the potential to cure patients, but the majority of patients are inoperable. A phase I/II study of hypofractionated high-precision radiotherapy for patients with liver cancer is open and, as part of the study, the toxicities and benefits of this treatment are being investigated. The treatment protocol involves the use of high-precision intensity modulated radiation, image guidance and breath hold radiation to minimize liver motion due to breathing.

The role of kV cone beam CT for image guidance is being investigated, as are novel methods of describing normal tissue complication probability following radiotherapy.
Comput Methods Biomech Biomed Engin. 2019 Mar 18;:1-14
Post A, Dawson L, Hoshizaki TB, Gilchrist MD, Cusimano MD
Comput Methods Biomech Biomed Engin. 2019 Mar 04;:1-13
Post A, Hoshizaki TB, Karton C, Clark JM, Dawson L, Cournoyer J, Taylor K, Oeur RA, Gilchrist MD, Cusimano MD
Pract Radiat Oncol. 2019 Feb 27;:
Dawson LA, Winter KA, Katz AW, Schell MC, Brierley J, Chen Y, Kopek N, Crane CH, Willett CG
Transplantation. 2019 Feb 18;:
Gorgen A, Rosales R, Sadler E, Beecroft R, Knox J, Dawson LA, Ghanekar A, Grant D, Greig PD, Sapisochin G
Int J Radiat Oncol Biol Phys. 2019 Mar 01;103(3):540-541
Barry A, Wong R, Dawson LA
Abdom Radiol (NY). 2019 Feb 01;:
Mastrocostas K, Jang HJ, Fischer S, Dawson LA, Munoz-Schuffenegger P, Sapisochin G, Kim TK
Lancet Oncol. 2018 Nov 22;:
Berlin A, Hodgson D, Dawson LA
Adv Radiat Oncol. 2018 Oct-Dec;3(4):662-672
McCulloch MM, Muenz DG, Schipper MJ, Velec M, Dawson LA, Brock KK
Semin Radiat Oncol. 2018 Oct;28(4):295-308
Toesca DAS, Barry A, Sapisochin G, Beecroft R, Dawson L, Owen D, Mouli S, Lewandowski R, Salem R, Chang DT
Technol Cancer Res Treat. 2018 Jan 01;17:1533033818790217
Schaub SK, Hartvigson PE, Lock MI, Høyer M, Brunner TB, Cardenes HR, Dawson LA, Kim EY, Mayr NA, Lo SS, Apisarnthanarax S

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Professor, Department of Radiation Oncology, University of Toronto
Staff Radiation Oncologist, Princess Margaret Cancer Centre