Laura A Dawson

Laura A Dawson, MD, FRCPC

The development of high-precision radiation techniques enables radiation to be investigated as a treatment for tumours previously unsuitable for radiotherapy due to proximity to critical adjacent normal tissues. An example is primary and metastatic liver cancer, a site where local therapy with surgery has the potential to cure patients, but the majority of patients are inoperable. A phase I/II study of hypofractionated high-precision radiotherapy for patients with liver cancer is open and, as part of the study, the toxicities and benefits of this treatment are being investigated. The treatment protocol involves the use of high-precision intensity modulated radiation, image guidance and breath hold radiation to minimize liver motion due to breathing.

The role of kV cone beam CT for image guidance is being investigated, as are novel methods of describing normal tissue complication probability following radiotherapy.
Surg Oncol Clin N Am. 2017 Oct;26(4):647-666
Sim HW, Knox J, Dawson LA
Int J Radiat Oncol Biol Phys. 2017 Oct 01;99(2):388-395
McPartlin A, Swaminath A, Wang R, Pintilie M, Brierley J, Kim J, Ringash J, Wong R, Dinniwell R, Craig T, Dawson LA
Semin Radiat Oncol. 2017 Oct;27(4):350-357
Munoz-Schuffenegger P, Ng S, Dawson LA
Adv Radiat Oncol. 2016 Jul-Sep;1(3):194-203
Coolens C, Driscoll B, Moseley J, Brock KK, Dawson LA
Radiother Oncol. 2017 Jun 28;:
Murray L, Longo J, Wan J, Chung C, Wang L, Dawson L, Milosevic M, Oza A, Brade A
Semin Radiat Oncol. 2017 Jul;27(3):247-255
Murray LJ, Dawson LA
Pract Radiat Oncol. 2017 Mar 09;:
Barry A, McPartlin A, Lindsay P, Wang L, Brierley J, Kim J, Ringash J, Wong R, Dinniwell R, Craig T, Dawson LA
Lancet Oncol. 2017 Apr;18(4):e192
Nabavizadeh N, Mitin T, Dawson LA, Hong TS, Thomas CR
Int J Radiat Oncol Biol Phys. 2017 Apr 01;97(5):939-946
Velec M, Haddad CR, Craig T, Wang L, Lindsay P, Brierley J, Brade A, Ringash J, Wong R, Kim J, Dawson LA
J Hepatol. 2017 Feb 28;:
Sapisochin G, Barry A, Doherty M, Fischer S, Goldaracena N, Rosales R, Russo M, Beecroft R, Ghanekar A, Bhat M, Brierley J, Greig PD, Knox JJ, Dawson LA, Grant DR

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Professor, Department of Radiation Oncology, University of Toronto
Staff Radiation Oncologist, Princess Margaret Cancer Centre