Jeffrey H Lipton

Jeffrey H Lipton, PhD, MD, FRCPC

I am involved in clinical research at the phase I, II and III levels on the therapy of chronic myeloid leukemia. This involves targeted therapy with kinase inhibitors, drugs that may target the CML stem cell and cells that are resistant to other therapies. The interest in targeted therapy extends into the phase II study of signal transduction inhibitors in the therapy of other diseases such as systemic mastocytosis and mast cell leukemia.

The second aspect of my clinical research involves outcome analysis in allogeneic stem cell transplant and the prevention and therapy of side effects. I am particularly interested in donor selection, graft types and therapy of chronic side effects. I am also interested in long term effects on patients who are out beyond the initial post transplant period.
Bone Marrow Transplant. 2018 Mar;53(3):334-338
Uhm J, Shin E, Michelis FV, Thyagu S, Viswabandya A, Lipton JH, Messner HA, Kim DDH
Eur Respir J. 2018 Mar 15;:
Hirama T, Brode SK, Beswick J, Law AD, Lam W, Michelis FV, Thyagu S, Viswabandya A, Lipton JH, Messner HA, Kim DDH, Marras TK
Expert Opin Emerg Drugs. 2018 Feb 25;:
Kavanagh S, Nee A, Lipton JH
Ann Intern Med. 2018 Feb 20;:
Mahon FX, Boquimpani C, Kim DW, Benyamini N, Clementino NCD, Shuvaev V, Ailawadhi S, Lipton JH, Turkina AG, De Paz R, Moiraghi B, Nicolini FE, Dengler J, Sacha T, Takahashi N, Fellague-Chebra R, Acharya S, Wong S, Jin Y, Hughes TP
Support Care Cancer. 2018 Feb 08;:
Devins GM, Mah K, Messner HA, Xenocostas A, Gauvin L, Lipton JH
Bone Marrow Transplant. 2017 Dec 21;:
Deotare U, Atenafu EG, Loach D, Michelis FV, Kim DD, Thyagu S, Lipton JH, Messner HA, Viswabandya A
Eur J Haematol. 2017 Dec 14;:
Aljasem HA, Messner HA, Lipton JH, Kim DDH, Viswabandya A, Thyagu S, Deotare U, Michelis FV
Eur J Haematol. 2017 Nov 23;:
Khalil MMI, Lipton JH, Atenafu EG, Gupta V, Kim DD, Kuruvilla J, Viswabandya A, Messner HA, Michelis FV
Cell Rep. 2016 10 18;17(4):1053-1070
Ebrahimi-Fakhari D, Saffari A, Wahlster L, Di Nardo A, Turner D, Lewis TL, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M
Pediatrics. 2017 Oct 30;:
Shearer WT, Lubin BH, Cairo MS, Notarangelo LD, SECTION ON HEMATOLOGY/ONCOLOGY, SECTION ON ALLERGY AND IMMUNOLOGY

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Professor of Medicine, University of Toronto