- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
The cardiomyocyte lineage is critical for optimization of stem cell therapy in a mouse model of myocardial infarction.
FASEB J. 2010 Apr;24(4):1073-81
Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue.
Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3329-34
In vivo detection of embryonic stem cell-derived cardiovascular progenitor cells using Cy3-labeled Gadofluorine M in murine myocardium.
JACC Cardiovasc Imaging. 2009 Sep;2(9):1114-22
Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications.
Cold Spring Harb Symp Quant Biol. 2008;73:101-10
Cell Stem Cell. 2009 Mar 06;4(3):198-9; author reply 202
Nat Biotechnol. 2008 Oct;26(10):1169-78
Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast.
Development. 2008 Oct;135(20):3447-58
Cancer Biol Ther. 2008 Sep;7(9):1341-7
Neuro Oncol. 2009 Apr;11(2):102-8
Senior Scientist, Princess Margaret Cancer Centre
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto