- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
Circ Arrhythm Electrophysiol. 2013 Feb;6(1):191-201
T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures.
Cell Rep. 2012 Dec 27;2(6):1722-35
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells.
Cardiovasc Res. 2013 Apr 01;98(1):125-35
Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation.
Cell Stem Cell. 2012 Jul 06;11(1):23-35
Semin Cell Dev Biol. 2012 Aug;23(6):701-10
Dev Cell. 2012 Jul 17;23(1):45-57
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics.
Biotechnol Bioeng. 2012 Apr;109(4):853-66
Regulated expression and role of c-Myb in the cardiovascular-directed differentiation of mouse embryonic stem cells.
Circ Res. 2012 Jan 20;110(2):253-64
The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells.
Diabetologia. 2012 Feb;55(2):358-71
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.
Nat Biotechnol. 2011 Oct 23;29(11):1011-8
Senior Scientist, Princess Margaret Cancer Centre
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto