- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies.
Cell Rep. 2019 Apr 09;27(2):599-615.e12
Cell. 2019 Jan 18;:
Neuron. 2018 Oct 24;100(2):424-435
Nat Commun. 2018 Oct 22;9(1):4383
Neuron. 2018 Aug 15;:
SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment.
Neuro Oncol. 2018 Apr 09;20(5):621-631
Reduced Baseline Airway Caliber Relates to Larger Airway Sensitivity to Rostral Fluid Shift in Asthma.
Front Physiol. 2017;8:1012
FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors.
Stem Cell Reports. 2018 Jan 09;10(1):87-100
Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance.
Stem Cell Res. 2017 Dec;25:107-114
Deprivation-Induced Homeostatic Spine Scaling In Vivo Is Localized to Dendritic Branches that Have Undergone Recent Spine Loss.
Neuron. 2017 Nov 15;96(4):871-882.e5
Senior Scientist, Princess Margaret Cancer Centre
Director, Research Institute, McEwen Stem Cell Institute
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto