- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes.
Blood. 2016 Jun 14;
Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis.
Nat Mater. 2016 Mar 7;
Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors.
Stem Cells. 2015 Jul;33(7):2148-57
Nat Commun. 2016;7:10312
Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair.
Stem Cell Reports. 2015 Oct 20;
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.
Nat Med. 2015 Oct 26;
New markers for tracking endoderm induction and hepatocyte differentiation from human pluripotent stem cells.
Development. 2015 Oct 22;
Mol Ther. 2015 Oct 7;
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.
Nat Commun. 2015;6:8391
A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17.
Stem Cell Reports. 2015 Aug 11;5(2):291-304
Senior Scientist, Princess Margaret Cancer Centre
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto