Fei-Fei Liu

Fei-Fei Liu, MD, FRCPC

Our lab is focused on several aspects of translational molecular oncology, including the development of biomarkers for head and neck cancers, high throughput screens to identify novel anti-cancer therapeutics and stem cell regenerative therapy. Using DNA, RNA and protein extracted from diagnostic human cancer samples, we are in the process of conducting multi-omic global expression analyses. Preliminary data are very promising, and in addition to identifying multi-dimensional predictive/prognostic signatures for improving cancer patient management, we are also studying their related pathways and biological functions in preclinical models of human cancers. Automated robotic screens are being used to identify corresponding novel anti-cancer compounds, and characterization of these potential new therapeutics is underway. Finally, we are also interested in understanding how adipose derived stem cells may aid in tissue regeneration after treatment with ionizing radiation.
J Hum Genet. 2016 Jul 7;
Kinoshita T, Yip KW, Spence T, Liu FF
Clin Oncol (R Coll Radiol). 2016 Apr 29;
Han K, Yap ML, Yong JH, Mittmann N, Hoch JS, Fyles AW, Warde P, Gutierrez E, Lymberiou T, Foxcroft S, Liu FF
Chin Clin Oncol. 2016 Apr;5(2):17
Spence T, Bruce J, Yip KW, Liu FF
Oncotarget. 2016 Apr 22;
Vishnubalaji R, Hamam R, Yue S, Al-Obeed O, Kassem M, Liu FF, Aldahmash A, Alajez NM
JAMA Oncol. 2016 Mar 24;
Bratman SV, Bruce JP, O'Sullivan B, Pugh TJ, Xu W, Yip KW, Liu FF
J Radiat Res. 2016 Mar 16;
Kwan JY, Psarianos P, Bruce JP, Yip KW, Liu FF
Oncotarget. 2016 Feb 26;
Shi W, Bruce J, Lee M, Yue S, Rowe M, Pintilie M, Kogo R, Bissey PA, Fyles A, Yip KW, Liu FF
Cancer Epidemiol. 2015 Dec 16;40:102-112
Chu KP, Habbous S, Kuang Q, Boyd K, Mirshams M, Liu FF, Espin-Garcia O, Xu W, Goldstein D, Waldron J, O'Sullivan B, Huang SH, Liu G
J Clin Oncol. 2015 Sep 8;
Bruce JP, Yip K, Bratman SV, Ito E, Liu FF
Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):536-9
Thomas CR, Bonner JA, Hahn SM, Lawrence TS, Liu FF, Formenti SC, Society of Chairs of Academic Radiation Oncology Programs

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Professor, Radiation Oncology, University of Toronto
Professor, Medical Biophysics, University of Toronto
Professor, Otolaryngology, University of Toronto
Chief, Radiation Medicine Program, Princess Margaret Cancer Centre
Chair, Radiation Oncology, University of Toronto