Our lab is focused on several aspects of translational molecular oncology, including the development of biomarkers for head and neck cancers, high throughput screens to identify novel anti-cancer therapeutics and stem cell regenerative therapy. Using DNA, RNA and protein extracted from diagnostic human cancer samples, we are in the process of conducting multi-omic global expression analyses. Preliminary data are very promising, and in addition to identifying multi-dimensional predictive/prognostic signatures for improving cancer patient management, we are also studying their related pathways and biological functions in preclinical models of human cancers. Automated robotic screens are being used to identify corresponding novel anti-cancer compounds, and characterization of these potential new therapeutics is underway. Finally, we are also interested in understanding how adipose derived stem cells may aid in tissue regeneration after treatment with ionizing radiation.
Oncogenesis. 2018 May 22;7(5):40
Bissey PA, Law JH, Bruce JP, Shi W, Renoult A, Chua MLK, Yip KW, Liu FF
J Proteome Res. 2018 May 02;:
Principe S, Mejia-Guerrero S, Ignatchenko V, Sinha A, Ignatchenko A, Shi W, Pereira K, Su S, Huang SH, O'Sullivan B, Xu W, Goldstein DP, Weinreb I, Ailles L, Liu FF, Kislinger T
Cancer Res. 2018 Apr 23;:
Ahmed MM, Coleman CN, Mendonca M, Bentzen S, Vikram B, Seltzer SM, Goodhead D, Obcemea C, Mohan R, Prise KM, Capala J, Citrin D, Kao G, Aryankalayil M, Eke I, Buchsbaum JC, G S Prasanna P, Liu FF, Le QT, Teicher B, Kirsch DG, Smart D, Tepper J,...
Int J Radiat Oncol Biol Phys. 2018 Feb 01;:
Kwan JYY, Su J, Huang SH, Ghoraie LS, Xu W, Chan B, Yip KW, Giuliani M, Bayley A, Kim J, Hope AJ, Ringash J, Cho J, McNiven A, Hansen A, Goldstein D, de Almeida JR, Aerts HJ, Waldron JN, Haibe-Kains B, O'Sullivan B, Bratman SV, Liu FF
Int J Radiat Oncol Biol Phys. 2018 Jan 09;:
Jones RD, Chapman CH, Holliday EB, Lalani N, Wilson E, Bonner JA, Movsas B, Kalnicki S, Formenti SC, Thomas CR, Hahn SM, Liu FF, Jagsi R, Society of Chairs of Academic Radiation Oncology Programs (SCAROP)
Curr Oncol. 2017 Dec;24(6):e518-e523
Hamilton JL, Foxcroft S, Moyo E, Cooke-Lauder J, Spence T, Zahedi P, Bezjak A, Jaffray D, Lam C, Létourneau D, Milosevic M, Tsang R, Wong R, Liu FF
J Healthc Manag. 2017 Sep/Oct;62(5):302-313
Holliday EB, Bonner JA, Formenti SC, Hahn SM, Kalnicki S, Liu FF, Movsas B, Fuller CD, Thomas CR
Lancet Oncol. 2017 May;18(5):e238
Bratman SV, Milosevic MF, Liu FF, Haibe-Kains B
Source Code Biol Med. 2017;12:1
Haider S, Waggott D, Lalonde E, Fung C, Liu FF, Boutros PC

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Professor, Radiation Oncology, University of Toronto
Professor, Medical Biophysics, University of Toronto
Professor, Otolaryngology, University of Toronto
Chief, Radiation Medicine Program, Princess Margaret Cancer Centre
Chair, Radiation Oncology, University of Toronto