Dr. Goligher is an Assistant Professor in the Interdepartmental Division of Critical Care Medicine at the University of Toronto and a Clinician Scientist at the University Health Network. After studying biochemistry and medicine at the University of British Columbia, he training in internal medicine and critical care medicine at the University of Toronto. He subsequently earned a doctoral degree in physiology from the University of Toronto, focusing on mechanisms of diaphragmatic dysfunction during mechanical ventilation. His research program is focused on characterizing the mechanisms and impact of injury in the lung and diaphragm during mechanical ventilation, and on employing innovative clinical trial designs to test lung and diaphragm-protective ventilation strategies.
Acute respiratory failure, acute respiratory distress syndrome, mechanical ventilation, respiratory physiology and clinical epidemiology.
Dr. Goligher is currently working on the following studies:
- ABS-MV – NCT03567564
- LANDMARK – NCT03612583
- DIASPORA – NCT03667027
- ALIVE – NCT03589482
- MYOTRAUMA – NCT03108118
- SNIFF III – NCT03129217
Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.
Lancet Respir Med. 2019 Jan 11;:
Withholding or withdrawing life support versus physician-assisted death: a distinction with a difference?
Curr Opin Anaesthesiol. 2018 Dec 06;:
Curr Opin Crit Care. 2018 Dec 05;:
Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure.
Lancet Respir Med. 2018 Nov 16;:
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.
Crit Care Med. 2018 Oct 30;:
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome and Posterior Probability of Mortality Benefit in a Post Hoc Bayesian Analysis of a Randomized Clinical Trial.
JAMA. 2018 Oct 22;:
Visualizing Heterogeneous Pulmonary Ventilation: Respiratory Failure Due to an Anterior Mediastinal Mass.
Am J Respir Crit Care Med. 2018 Jun 20;:
Avoiding Respiratory and Peripheral Muscle Injury During Mechanical Ventilation: Diaphragm-Protective Ventilation and Early Mobilization.
Crit Care Clin. 2018 Jul;34(3):357-381
Diaphragm function and weaning from mechanical ventilation: an ultrasound and phrenic nerve stimulation clinical study.
Ann Intensive Care. 2018 Apr 23;8(1):53
Ann Am Thorac Soc. 2018 Mar 27;:
Scientist, Toronto General Hospital Research Institute (TGHRI)
Assistant Professor, Interdepartmental Division of Critical Care Medicine, University of Toronto