David Alter, MD, PhD, FRCPC

Senior Scientist, Toronto Rehabilitation Institute (TRI)
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Keywords: acute myocardial infarction, behavioural determinants, cohort studies, exercise rehabilitation, health services research, music, population health, prognosis, socioeconomic status, clinical outcomes

Dr. Alter maintains an active community cardiology practice in Milton Ontario (Milton Cardiac Care) and is the founder of a social purpose organization called Vigour Projects, whose mission is to improve the health of communities through music.
Dr. Alter's research spans across many disciplines including cardiovascular health services and outcomes, clinical epidemiology and social determinants, cardiac rehabilitation and more recently, music and medicine. He has published over 125 scholarly peer-reviewed papers in prestigious journals such as the New England Journal of Medicine and the Journal of the American Medical Association. Dr. Alter has also received funding from various agencies including the Heart and Stroke Foundation of Ontario.

Comparative Effectiveness of the Core Components of Cardiac Rehabilitation on Mortality and Morbidity: A Systematic Review and Network Meta-Analysis.
J Clin Med. 2018 Dec 04;7(12):
Kabboul NN, Tomlinson G, Francis TA, Grace SL, Chaves G, Rac V, Daou-Kabboul T, Bielecki JM, Alter DA, Krahn M
The Health Economics of Myocardial Infarction: Black Boxes and Black Holes.
Can J Cardiol. 2018 Oct;34(10):1253-1255
Stone JA, Alter DA
Trends in the incidence and outcomes of patients with aortic stenosis hospitalization.
Am Heart J. 2018 May;199:144-149
Czarnecki A, Qiu F, Koh M, Alter DA, Austin PC, Fremes SE, Tu JV, Wijeysundera HC, Yan AT, Ko DT
Projected Real-World Effectiveness of Using Aggressive Low-Density Lipoprotein Cholesterol Targets Among Elderly Statin Users Following Acute Coronary Syndromes in Canada.
J Am Heart Assoc. 2018 May 12;7(10):
Alter DA, Tu JV, Koh M, Jackevicius CA, Austin PC, Rezai MR, Bhatia RS, Johnston S, Udell JA, Ko DT
Is promoting six hours of standing an appropriate public health message?
Eur J Prev Cardiol. 2018 Jan 01;:2047487318763430
Biswas A, Smith PM, Alter DA
Association of high-density lipoprotein cholesterol with non-fatal cardiac and non-cardiac events: a CANHEART substudy.
Open Heart. 2017;4(2):e000731
Wijeysundera HC, Koh M, Alter DA, Austin PC, Jackevicius CA, Tu JV, Ko DT
When Do We Decide That Generic and Brand-Name Drugs Are Clinically Equivalent? Perfecting Decisions With Imperfect Evidence.
Circ Cardiovasc Qual Outcomes. 2017 Oct;10(10):
Alter DA
Tracking Our Physical Inactivity and Progression to Death: Is This Evolutionary Stagnation?
Ann Intern Med. 2017 Sep 12;:
Alter DA
Music for anxiety reduction in patients undergoing cardiac catheterization: A systematic review and meta-analysis of randomized controlled trials.
Complement Ther Clin Pract. 2017 Aug;28:122-130
Jayakar JP, Alter DA
The energy expenditure benefits of reallocating sedentary time with physical activity: a systematic review and meta-analysis.
J Public Health (Oxf). 2017 Jun 07;:1-9
Biswas A, Oh PI, Faulkner GE, Bonsignore A, Pakosh MT, Alter DA

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Senior Scientist, Toronto Rehabilitation Institute (TRI)

Senior Scientist, Institute for Clinical Evaluative Sciences
Associate Professor of Medicine, University of Toronto
Cross appointment to the Department of Health Policy, Management, and Evaluation, University of Toronto
Adjunct Scientist, Li Ka Shing Knowledge Institute, St. Michael's Hospital