Brian O’Sullivan is a Professor in the Department of Radiation Oncology and in the Department of Otolaryngology / Head and Neck Surgery at the University of Toronto. He holds the Bartley-Smith/Wharton Chair in Radiation Oncology in the Department of Radiation Oncology at the Princess Margaret Hospital. He received his medical degree from the National University of Ireland at University College Dublin in 1976, and completed internship and general internal medicine at St. Vincent’s Hospital in Dublin, and a fellowship in medical oncology, and a residency and clinical fellowship in radiation oncology at Princess Margaret Hospital.
Professor O’Sullivan is the immediate past-Chair of the Head and Neck Oncology Committee of the Canadian Clinical Trials Group (CCTG) and current co-Chair of the US NCI Head and Neck Steering Committee of the Coordinating Center for Clinical Trials, CTEP. He is the recipient of numerous international awards such as the O.Harold Warwick Prize, the ESTRO Honorary Membership Award, the Fellow of ASTRO Award, the Juan Del Regato Gold Medal, the Inaugural Stiefel Lectureship and the Gilbert Fletcher Distinguished Professor Lecturer at MD Anderson Cancer Centre, and the Ira Spiro Distinguished Memorial Lecturer Award at Harvard Medical School.

He has published almost 350 peer reviewed papers, more than 50 book chapters, and written or edited 6 oncology textbooks. He is a Commissioner, International Commission on Radiation Units & Measurements (ICRU). He is a member of the TNM Committee of the Union for International Cancer Control (UICC), Chair of the UICC Prognostic Factors Sub-Committee, Editor-in-Chief of the UICC Manual of Clinical Oncology, and the UICC liaison to the American Joint Committee on Cancer (AJCC) for head and neck cancer, and bone and soft tissue sarcoma.

His interests include the biology and clinical behavior of sarcoma and head and neck cancer, cancer staging and prognostic factor, risk stratification and treatment optimization, clinical trial and translational research, quality improvement and global cancer control.
  • Tumor biology and clinical behavior of HPV-related and unrelated head and neck cancers
  • Risk stratification and customization of treatments for head and neck cancer and soft tissue sarcoma
  • Treatment optimization and innovation for head and neck cancer and soft tissue sarcoma
  • Cancer staging and clinical trials
  • Radiotherapy quality improvement and global cancer control
Int J Cancer. 2018 Sep 07;:
Lee VH, Kwong DL, Leung TW, Choi CW, O'Sullivan B, Lam KO, Lai V, Khong PL, Chan SK, Ng CY, Tong CC, Ho PP, Chan WL, Wong LS, Leung DK, Chan SY, So TH, Luk MY, Lee AW
Int J Radiat Oncol Biol Phys. 2018 Oct 01;102(2):340-352
McDowell LJ, Rock K, Xu W, Chan B, Waldron J, Lu L, Ezzat S, Pothier D, Bernstein LJ, So N, Huang SH, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Ringash J
AJNR Am J Neuroradiol. 2018 Aug 30;:
Weimar EAM, Huang SH, Lu L, O'Sullivan B, Perez-Ordonez B, Weinreb I, Hope A, Tong L, Goldstein D, Irish J, de Almeida JR, Bratman S, Xu W, Yu E
J Med Internet Res. 2018 Jul 16;20(7):e239
O'Sullivan B, Alam F, Matava C
Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):763-764
O'Sullivan B, Waldron J
Int J Radiat Oncol Biol Phys. 2018 May 17;:
Almulla A, Noel CW, Lu L, Xu W, O'Sullivan B, Goldstein DP, Hope A, Perez-Ordonez B, Weinreb I, Irish J, Gullane P, Chepeha D, Tong L, Yu E, Huang SH
Oral Oncol. 2018 Jul;82:162-167
Horowitz G, Hosni A, Yu E, Xu W, Lu L, Au M, Dixon PR, Brown D, Chepeha DB, Gilbert RW, Goldstein DP, Gullane PJ, Irish JC, Bayley A, Cho J, Giuliani M, Huang SH, Hope A, Kim J, O'Sullivan B, Ringash J, Waldron J, Weinreb I, Perez-Ordonez B, Bratman SV...
Int J Radiat Oncol Biol Phys. 2018 May 02;:
Ng WT, Tung SY, Lee V, Ngan RKC, Choi HCW, Chan LLK, Leung TW, Siu LL, Lu TX, Tan T, Tan EH, Sze HCK, Ng AWY, Yiu HHY, O'Sullivan B, Chappell R, Lee AWM
J Clin Oncol. 2018 Jun 07;:JCO2018787325
Gundle KR, Griffin AM, Dickson BC, Chung PW, Catton CN, O'Sullivan B, Wunder JS, Ferguson PC
JAMA Oncol. 2018 May 17;:
Liu X, Zhang Y, Tang LL, Le QT, Chua MLK, Wee JTS, Lee NY, O'Sullivan B, Lee AWM, Sun Y, Ma J



Radiation Oncology Chair, Head and Neck Steering Committee, US National Cancer Institute
Commissioner, International Commission on Radiation Units & Measurements (ICRU)
Prognostic Factors Committee Chair, Union for International Cancer Control (UICC), TNM Classification of Malignant Tumours
Clinician-Scientist, Ontario Association of Radiation Oncologist, Ministry of Health
Clinician-Scientist, Ontario Cancer Institute, University Health Network, Toronto
Associate Member, Graduate Faculty, Institute of Medical Science, University of Toronto