UHN Studies Named as Top Cancer Discoveries

Posted On: January 26, 2015
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UHN researchers Drs. Dick and Bristow (L-R) authored publications that were honoured by the Canadian Cancer Society.
Two research findings by UHN scientists appear in the list of the Top 10 Canadian Cancer Society-funded research of 2014: one by McEwen Researcher Dr. John Dick and the other by PM Senior Scientist Dr. Robert Bristow. The studies are recognized by the Society for transforming our understanding of cancer.

Dr. Dick’s article appeared in the journal Nature and described the role of the DNMT3A gene as an important indicator of the earliest stages of leukemia (a cancer of the blood). His research team found that blood cells carrying mutations in this gene were ancestors of cells that would eventually become leukemic. These cells may help identify people who are likely to develop disease and the findings offer a new treatment strategy by targeting pre-leukemic cells. Read more about the study here.

The second study, led by Dr. Bristow, revealed a new genetic test that is capable of predicting prostate cancer recurrence. The test will help identify people that require more aggressive treatments and avoid over-treating those who do not. The study was published in Lancet Oncology.

The full list of the Top 10 Society-funded research discoveries can be viewed here.

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