We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
Ethical surgical placebo-controlled trials of deep brain stimulation for treatment-resistant anorexia nervosa - Authors' reply.
Lancet Psychiatry. 2017 Jun;4(6):442
Epilepsy Behav. 2017 May 26;71(Pt A):79-84
Entorhinal Cortical Deep-Brain Stimulation Rescues Memory Deficits In Both Young And Old Mice Genetically Engineered To Model Alzheimer's Disease.
Neuropsychopharmacology. 2017 May 25;:
Curr Opin Neurol. 2017 May 13;:
The Spectrum of Altmetrics in Neurosurgery: The Top 100 "Trending" Articles in Neurosurgical Journals.
World Neurosurg. 2017 May 03;:
Ann Neurol. 2017 Apr 10;:
Neurosurg Focus. 2017 Apr;42(VideoSuppl2):Intro
Your algorithm might think the hippocampus grows in Alzheimer's disease: Caveats of longitudinal automated hippocampal volumetry.
Hum Brain Mapp. 2017 Mar 15;:
Neurocognitive Predictors of Response in Treatment Resistant Depression to Subcallosal Cingulate Gyrus Deep Brain Stimulation.
Front Hum Neurosci. 2017;11:74
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto