We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
Brain Stimul. 2018 Jan 02;:
A Prospective Trial of Magnetic Resonance guided Focused Ultrasound Thalamotomy for Essential Tremor: Results at the 2-year Follow-up.
Ann Neurol. 2017 Dec 19;:
Chronic deep brain stimulation in an Alzheimer's disease mouse model enhances memory and reduces pathological hallmarks.
Brain Stimul. 2017 Nov 23;:
Brain. 2017 Dec 11;:
Mov Disord. 2017 Nov 30;:
Stopping and slowing manual and spoken responses: Similar oscillatory signatures recorded from the subthalamic nucleus.
Brain Lang. 2017 Nov 07;176:1-10
J Neurosurg. 2017 Nov 10;:1-8
Brain Stimul. 2017 Oct 12;:
Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial.
Lancet Psychiatry. 2017 Oct 04;:
Mov Disord. 2017 Sep 28;:
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto