We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
J Neurosurg Sci. 2012 Dec;56(4):341-4
Spatial extent of β oscillatory activity in and between the subthalamic nucleus and substantia nigra pars reticulata of Parkinson's disease patients.
Exp Neurol. 2013 Jul;245:60-71
Mov Disord. 2012 Nov;27(13):1598-605
Real-time two-dimensional asynchronous control of a computer cursor with a single subdural electrode.
J Spinal Cord Med. 2012 Sep;35(5):382-91
Stereotact Funct Neurosurg. 2012;90(6):347-55
Mov Disord. 2012 Sep 1;27(10):1304-7
J Neurosurg Sci. 2012 Sep;56(3):209-20
Electrical stimulation of the inferior thalamic peduncle in the treatment of major depression and obsessive compulsive disorders.
World Neurosurg. 2013 Sep-Oct;80(3-4):S30.e17-25
Brain Stimul. 2013 May;6(3):221-30
World Neurosurg. 2013 Sep-Oct;80(3-4):S28.e1-8
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto