We work on novel surgical approaches to treat Parkinson's disease, depression and Alzheimer's disease. We use brain imaging, electrophysiology and surgical techniques. The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.
Predicting Lesion Size by Accumulated Thermal Dose in MR-Guided Focused Ultrasound for Essential Tremor.
Med Phys. 2018 Aug 11;:
Hybrid deep brain stimulation system to manage stimulation-induced side effects in essential tremor patients.
Parkinsonism Relat Disord. 2018 Jul 23;:
Imaging alone versus microelectrode recording-guided targeting of the STN in patients with Parkinson's disease.
J Neurosurg. 2018 Aug 03;:1-6
Neurosurg Focus. 2018 Aug;45(2):E1
Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation.
J Alzheimers Dis. 2018 Jun 09;:
Physiological mechanisms of thalamic ventral intermediate nucleus stimulation for tremor suppression.
Brain. 2018 Jun 05;:
Subthalamic Nucleus Visualization on Routine Clinical Preoperative MRI Scans: A Retrospective Study of Clinical and Image Characteristics Predicting Its Visualization.
Stereotact Funct Neurosurg. 2018 May 30;:1-7
Trends Neurosci. 2018 May 04;:
J Neurosurg. 2018 May 04;:1-5
Brain Stimul. 2018 Apr 13;:
Senior Scientist, Krembil Research Institute (Krembil)
Affiliated Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Dan Family Chair in Neurosurgery, University of Toronto
R.R. Tasker Chair in Stereotactic and Functional Neurosurgery
Tier 1 Canada Research Chair in Neuroscience
Professor, Department of Surgery, University of Toronto
University Professor, University of Toronto