UHN has received a historic $27.1 million in total funding from the CIHR Project Grant Fall 2025 competition. The funding supports 31 research teams across UHN, including 24 full research grants and seven priority announcements.
The CIHR Project Grant program is designed to offer scientists, at any stage of their careers, funding for ideas with the greatest potential to advance health-related knowledge, research methodologies, patient care, and overall outcomes. In this recent competition, CIHR has invested approximately $413 million to fund 421 research grants across Canada. An additional 83 priority announcement grants were funded over $9.7 million, and 17 supplemental prizes were awarded a total of $450,000.
Among the UHN-funded projects are investigations into a new therapeutic target for acute myeloid leukemia (led by Dr. Steven Chan) and how BRCA2 mutations alter breast tissue before cancer begins (led by Dr. Frederico Gaiti). Other teams are studying immune pathways that are associated with age-related memory loss (led by Dr. Valeria Ramaglia) and developing new therapeutic strategies for retinal neurodegeneration, like glaucoma (led by Dr. Jeremy Sivak).
Some additional projects include determining which kidney transplant patients are most at risk of transplant failure (led by Dr. Ana Konvalinka) and identifying the challenges of personal support workers in Ontario to improve training, policy, and workforce stability (led by Drs. Nicole Woods, Sandra McKay, Maria Mylopoulos, and Stella Ng).
This funding is fueling innovations that lead to earlier diagnoses, more effective treatments, and stronger health systems. Thanks to CHIR’s support, UHN researchers are turning discoveries into real-world impact and helping create A Healthier World for all. Congratulations to all the awardees!
See the full list of the awarded projects here.