Lora M Giangregorio, PhD

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https://orcid.org/0000-0002-3739-1805
The aim of our research team is to reduce the burden of osteoporotic fractures. We use medical imaging technologies to explore bone and muscle responses to activity or neurologic impairment, and evaluate new methods for image analysis. We conduct epidemiologic studies to inform fracture risk assessment algorithms. We conduct clinical trials to investigate the effects of exercise interventions for reducing fracture risk in high risk individuals. We conduct studies to investigate methods for increasing participation in safe and effective physical activity in older adults. We actively translate our research into practice by liaising with government and non-profit organizations and linking with community-based programs. For example, our research team has worked with Osteoporosis Canada to develop BoneFit, a two-day workshop for physiotherapists and kinesiologists on appropriate assessment and exercise prescription for individuals with osteoporosis. We also led the development of the Too Fit To Fracture Exercise and Physical Activity Recommendations for Individuals with Osteoporosis.

Ongoing research projects in our lab include the following:
  • A longitudinal study of bone health and body composition in individuals with neurological impairment due to spinal cord injury (SCI)
  • Studies evaluating medical imaging techniques for assessment of bone quality, muscle size and fatty infiltration
  • A multicentre randomized controlled trial of home exercise in women with osteoporotic spine fractures
  • Primary care-based physical activity intervention for older adults
  • Development of a fracture risk assessment algorithm for implementation in long term care
  • Rehabilitation and quality indicators in long term care
  • Knowledge translation research in partnership with Osteoporosis Canada and the Canadian Osteoporosis Patient Network
Geriatrics (Basel). 2018 Jul 07;3(3):
Lee L, Patel T, Hillier LM, Locklin J, Milligan J, Pefanis J, Costa A, Lee J, Slonim K, Giangregorio L, Hunter S, Keller H, Boscart V
Can J Aging. 2019 Apr 05;:1-17
Gibbs JC, McArthur C, Milligan J, Clemson L, Lee L, Boscart VM, Heckman G, Stolee P, Giangregorio LM
Arch Osteoporos. 2019 Feb 28;14(1):27
Ziebart C, Adachi JD, Ashe MC, Bleakney RR, Cheung AM, Gibbs JC, Hill KD, Kendler DL, Khan AA, Kim S, McArthur C, Mittmann N, Papaioannou A, Prasad S, Scherer SC, Thabane L, Wark JD, Giangregorio LM
J Bone Miner Res. 2019 Jan;34(1):3-21
Ebeling PR, Akesson K, Bauer DC, Buchbinder R, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML
BMC Geriatr. 2018 Dec 27;18(1):320
Negm AM, Ioannidis G, Jantzi M, Bucek J, Giangregorio L, Pickard L, Hirdes JP, Adachi JD, Richardson J, Thabane L, Papaioannou A
J Clin Densitom. 2018 Sep 22;:
Lewiecki EM, Bilezikian JP, Giangregorio L, Greenspan SL, Khosla S, Kostenuik P, Krohn K, McClung MR, Miller PD, Pacifici R
Pilot Feasibility Stud. 2018;4:137
El-Kotob R, Giangregorio LM
Osteoporos Int. 2018 Aug 08;:
Giangregorio LM, Gibbs JC, Templeton JA, Adachi JD, Ashe MC, Bleakney RR, Cheung AM, Hill KD, Kendler DL, Khan AA, Kim S, McArthur C, Mittmann N, Papaioannou A, Prasad S, Scherer SC, Thabane L, Wark JD

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Associate Professor, Department of Kinesiology, University of Waterloo
Affiliated Scientist, Geriatric Education and Research in Aging Sciences Centre