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Technology Transfer

Featured Technologies
Available for Licensing / Transfer

Below we describe some of the technologies that have been developed by UHN investigators. These inventions have been assessed by our office and screened for development potential and marketability. View: Therapeutics, Delivery Strategies, Medical Devices, Cell Lines, Antibodies, Research Tools, Software or Diagnostics.

 

Therapeutics

UHN

Inventor(s)

Technology Description

Publication

Link

One Page

Overview

L. Zhang; K, Young, M. Han

Novel T-Cell Immunotherapy

Link Link
J. Dick; E. Lechman; K. Hope MicroRNA-126 for Enhancing Stem Cell Engraftment and Monitoring the Treatment of Acute Myeloid Leukemia Link Link
E. Ito; F-F. Liu Enhancing Sensitivity to Radiotherapy and Chemotherapy of Head and Neck Cancer Link Link
A. Schimmer; et al Clioquinol Analogues for Treatment of Lymphoid Malignancies Link Link
A. Schimmer Combination Therapy using a Clioquinol Analogue and Bortezomib (Velcade) for Treatment of Lymphoid Malignancies Link Link
A. Schimmer; Y. Eberhard Ciclopirox Olamine in Combination with Cytarabine for Treatment of Lymphoid Malignancies Link Link
J. Medin; C. Paige IL-12 Immunotherapy for the Treatment of Cancer Link Link
J. Medin; Andrea McCart Immunotherapy for Cancer via Lentiviral Mediated
Cancer Antigen Administration
Link Link
A. Schimmer; et al Ivermectin in Combination with Cytarabine and/or Daunorubicin for Treatment of Lymphoid Malignancies Link Link
L. Kotra; A.Bello; E. Pai; C. Paige ODCase Inhibitors as Novel Anti-Cancer Agents Link Link
A. Schimmer; et al Flubendazole in Combination with Vinca Alkaloids for the Treatment of Leukemia Link Link
J. Dick; et al Leukemia and Hematopoietic Stem Cell Signatures
for Predicting Survival of Patients Having Acute Myeloid Leukemia
Link Link
L. Penn; A. Schimmer; A. Pandyra Treating Cancer with Statins and Dipyridamole Link Link
M. Fehlings; S. Robins The Therapeutic Use of IgG as a Neuroprotective Agent Link Link
M. Erwin; R. Inman; M. Fehlings Notochordal Cells for Treatment of Degenerative Disk Diseases Link Link
S. Berger Novel Method for Increasing Antibody Production Link Link
I. Crandall; W. Szarek Novel Antibiotic Agents Link Link
E.Fish; L.Kotra Peptide Mimetics for Treatment of Autoimmune and Viral Diseases Link Link
L. Kotra; K. Kain; E. Pai ODCase Inhibitors as Novel Anti-Malarial Drugs Link Link
K. Kain; L. Serghides Treatment for Severe and Cerebral Malaria Link Link
I.Crandall; K. Kain; R. Reithmeier; J. Charuk Malaria Drug Resistance Reversal Agent Link Link
I. Crandall; W. Szarek Small Molecule Malaria Invasion Inhibitors Link

Link

[Contact]

 

Delivery Strategies

UHN

Inventor(s)

Technology Description

Publication

Link

One Page

Overview

J. Chen; Z. Zhang; I. Corbin; G Zheng Multifunctional Nanoparticles for Targeted Drug Delivery of Cancer Therapeutics Link Link
J. Gariepy Loligomers: Targeted Intracellular Drug Delivery Vehicles Link Link

 

Medical Devices

UHN

Inventor(s)

Technology Description

Publication

Link

One Page

Overview

D. Galbraith, R. Heaton, M. Islam, D. Jaffray, B. Norrlinger, J. Smale Integrated Quality Monitor for Independent RT Verification Link Link
B. Wilson, A. Kim Sub-Surface Fluorescence Topography for Depth-resolved Fluorescence of Buried Pathologies Link Link
D. Jaffray, J. Siewerdsen, R. Weersink, A. Hope, A. Kashigar, M. Daly, J. Eubank, J. Cho Endoscopy + CT Multi-modal System for Radiation Therapy Treatment Planning Link Link
C. Coolens, H. Keller Calibration Phantom/Software for Dynamic Contrast MR/CT Imaging Link Link
L. White, M. Sussman, G. Andreisek, N. Young Synthetic Echo-Time Viewing Technique and Software for MR Imaging Link Link
D. Letourneau, M. Sharpe, D. Jaffray Automated IMRT Beam Model Commissioning Platform for Treatment Planning Systems Link Link
B. Wilson, A. Kim In-Vivo Fiberoptic Probe for Intra-operative Fluorescence Quantification in Tissue Link Link
Y-B Cho, M. Islam, D. Jaffray, M. van Prooijen, A. Zhang Head Frame Collision Avoidance and Virtual Planning Software for Gamma Knife® Link Link
B. Norrlinger, M. Islam, R. Heaton Web-Based Barometer and Thermometers for Radiation Therapy QA Link Link
B. Norrlinger, T. Hammer, G. Parsons, D. Jaffray, M. Islam LINAC Monitoring System Link Link
G. Disney, D. Jaffray, T. Michaelson, S. Rose, M. Sharpe Web-Publishing - Paperless Radiation Treatment Plan Review and Approval Link Link
T. Michaelson, B. Guibord, D. Payne E-Booking -Order Entry and Work-Flow Software for Radiation Oncology Clinics Link Link
G. Disney, M. Sharpe, P. Homer, I. Svistoun Lightweight Web-Based DICOM RT Viewer Link Link
R. DaCosta; B. Wilson; K. Zhang Hand-held Digital Imaging Platform for Wound-Care and Other Applications Link Link
M. Sherar; C. McCann Coil-RFA: Novel Radio-Frequency Ablation Technology for Treatment of Solid Tumors Link Link
M.Islam; et al Tandem Imaging System: Real-time Imaging During Radiation Therapy Treatment Link Link
M. Sussman; T. Roberts Motion Compensation in MRI: Navigator Echo Link Link
N. Munce; V. Yang; A. Thind; B. Courtney A Forward-viewing Intravascular Imaging and Guided Therapeutic Intervention Link Link
J. Barfett; T. Krings; D. Mikulis 3D CT Images Reconstructed from 4D CT Data Link Link
D. Jaffray; J. Hoisak; M. Kaus; T. Purdie 4D CT capability for 3D CT scanners Link Link
A. Rink; D. Jaffray; A. Vitkin Real-Time Radiochromic Dosimeter Link Link
S. Burch; B. Wilson; S. Bisland Bone Cancer PDT Treatment Device

Link Link
A. Bogaards; B. Wilson Fluorescence Quantification for Image Guided Surgery Link Link
Y-B. Cho; et al Stereotactic Radiosurgery Quality Assurance Phantom Link Link
J. Cafazzo; et al Bluetooth/USB Adapter for Medical Devices Link Link
J. Cafazzo;et al Mobile Phone Disease Management Link Link

[Contact]

 

Cell Lines

UHN

PI

Cell Line

Publication

Link

Abhijit Guha PTEN deficient ES cells  
Abhijit Guha Tetracycline inducible human glioma cell lines

1 - Link

2 - Link

3 - Link

Andres Lozano SH-SY5Y Stable Cell lines

Link

Jiang Liu H460 SM lung cancer cell line  
Shuzo Sugita Munc18-1 knockdown PC12 cells

Link

Shuzo Sugita Munc18-1 and -2 double knockdown PC12 cells

Link

Shuzo Sugita CAPS1 knockdown PC12 cells

Link

Armand Keating EM2eGFPluc

[Contact]  [Biological MTA - non-profit only]

 

Antibodies

UHN Inventor(s) Antibody Exclusive/Non-exclusive License

Clonality

Publication

Link

H. Okada antibodies for mouse Bat3 (rabbit) non-exclusive Polyclonal Link
C. Virtanen; M. Takahashi; J. Paris antibodies for mouse DAPR (rabbit) non-exclusive Polyclonal Link

[Contact] [Antibody License Agreement]

 

Diagnostics

UHN

Inventor(s)

Technology Description

Publication

Link

One Page

Overview

D. Jaffray; et al Multi-Modal Imaging Contrast Agent Link Link
M-S. Tsao; et al Genomic Markers for Malignant Progression in Pulmonary Adenocarcinoma with Bronchioloalveolar Features Link Link
S. Keshavjee; T. Waddell; M.Y. Liu Genomic Signature for Lung Transplant Viability Link Link
D. Kelvin; M.J. Cameron; D. Persad Early SARS Infection, Detection, and Prognosis Link Link
L. Lilge; B. Wilson; M. Simick Optical Breast Spectroscopy for Cancer Risk Assessment Link Link
K. Kain; W. Liles; F. Lovegrove Diagnostic and Prognostic Markers of Severe and Cerebral Malaria Link Link
P. Liu;  S. Arab; L. Zhang Peripheral Blood Marker that Distinguishes
Systolic and Diastolic Heart Failure
Link Link
L. Penn; P. Boutros; J. Clendening Molecular Signatures for Statin Sensitivity
in Multiple Myeloma Patients
Link Link

[Contact]


Research Tools

UHN

Inventor(s)

Technology Description

Publication

Link

One Page

Overview

J. Gariepy; A. McCluskey; G. Poon Rapid, High-Purity, Low-Cost Purification System for
Recombinant Proteins
Link Link
G. Privé Protein Stabilizing Detergent Link Link
N. Chirgadze; J. Miller; R.Lam, K. Johns Crystallization Device for High-Throughput Visual
Inspection and X-Ray Diffraction Analysis
Link Link

[Contact]

 


Software

UHN Copyright Software Name

Field of Use

Link/ Description

       2004 eCancerCare: Streamlining data collection for effective disease management and research Synoptic reporting, chronic disease patient managment tool, cancer care Link
       2005 SIMS Whiteboard Patient, physician, nurse tracking system Link
       2005 NAViGaTOR and I2D: Gene and Protein Integration Database and Graphing Software Network visualization and analysis of Protein-Protein interactions Link
       2005 Media Tracker Software Public Relations, Communications Link
       2005 Tuberculosis Management Database Tuberculosis/Infectious Disease Clinics Link
       2005 EMITT: Electronic Medication Information Transfer Tool Medication Reconciliation Link
   2008
Patient Relations Training DVD Patient Relations, Communications Link
      2005 The Lupus Health Passport Patient Relations, Communications Link

[Contact]

 

   
 
 
 
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