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Featured Technologies
Available for Licensing / Transfer
Below we describe some of the technologies that have been
developed by UHN investigators. These inventions have been assessed by our office and screened for
development potential and marketability. View: Therapeutics, Delivery Strategies, Medical Devices, Cell Lines, Antibodies, Research Tools, Software or Diagnostics.
Therapeutics
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| L. Zhang; K, Young, M. Han |
Novel T-Cell Immunotherapy |
Link |
Link |
| J. Dick; E. Lechman; K. Hope |
MicroRNA-126 for Enhancing Stem Cell Engraftment and Monitoring the Treatment of Acute Myeloid Leukemia |
Link |
Link |
| E. Ito; F-F. Liu |
Enhancing Sensitivity to Radiotherapy and Chemotherapy of Head and Neck Cancer |
Link |
Link |
| A. Schimmer; et al |
Clioquinol Analogues for Treatment of Lymphoid Malignancies |
Link |
Link |
| A. Schimmer |
Combination Therapy using a Clioquinol Analogue and Bortezomib (Velcade) for Treatment of Lymphoid Malignancies |
Link |
Link |
| A. Schimmer; Y. Eberhard |
Ciclopirox Olamine in Combination with Cytarabine for Treatment of Lymphoid Malignancies |
Link |
Link |
| J. Medin; C. Paige |
IL-12 Immunotherapy for the Treatment of Cancer |
Link |
Link |
| J. Medin; Andrea McCart |
Immunotherapy for Cancer via Lentiviral Mediated
Cancer Antigen Administration |
Link |
Link |
| A. Schimmer; et al |
Ivermectin in Combination with Cytarabine and/or Daunorubicin for Treatment of Lymphoid Malignancies |
Link |
Link |
| L. Kotra; A.Bello; E. Pai; C. Paige |
ODCase Inhibitors as Novel Anti-Cancer Agents |
Link |
Link |
| A. Schimmer; et al |
Flubendazole in Combination with Vinca Alkaloids for the Treatment of Leukemia |
Link |
Link |
| J. Dick; et al |
Leukemia and Hematopoietic Stem Cell Signatures
for Predicting Survival of Patients Having Acute Myeloid Leukemia |
Link |
Link |
| L. Penn; A. Schimmer; A. Pandyra |
Treating Cancer with Statins and Dipyridamole |
Link |
Link |
| M. Fehlings; S. Robins |
The Therapeutic Use of IgG as a Neuroprotective Agent |
Link |
Link |
| M. Erwin; R. Inman; M. Fehlings |
Notochordal Cells for Treatment of Degenerative Disk Diseases |
Link |
Link |
| S. Berger |
Novel Method for Increasing Antibody Production |
Link |
Link |
| I. Crandall; W. Szarek |
Novel Antibiotic Agents |
Link |
Link |
| E.Fish; L.Kotra |
Peptide Mimetics for Treatment of Autoimmune and Viral Diseases |
Link |
Link |
| L. Kotra; K. Kain; E. Pai |
ODCase Inhibitors as Novel Anti-Malarial Drugs |
Link |
Link |
| K. Kain; L. Serghides |
Treatment for Severe and Cerebral Malaria |
Link |
Link |
| I.Crandall; K. Kain; R. Reithmeier; J. Charuk |
Malaria Drug Resistance Reversal Agent |
Link |
Link |
| I. Crandall; W. Szarek |
Small Molecule Malaria Invasion Inhibitors |
Link |
Link
|
[Contact]
Delivery Strategies
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| J. Chen; Z. Zhang; I. Corbin; G Zheng |
Multifunctional Nanoparticles for Targeted Drug Delivery of Cancer Therapeutics |
Link |
Link |
| J. Gariepy |
Loligomers: Targeted Intracellular Drug Delivery Vehicles |
Link |
Link |
Medical Devices
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| D. Galbraith, R. Heaton, M. Islam, D. Jaffray, B. Norrlinger, J. Smale |
Integrated Quality Monitor for Independent RT Verification |
Link |
Link |
| B. Wilson, A. Kim |
Sub-Surface Fluorescence Topography for Depth-resolved Fluorescence of Buried Pathologies |
Link |
Link |
| D. Jaffray, J. Siewerdsen, R. Weersink, A. Hope, A. Kashigar, M. Daly, J. Eubank, J. Cho |
Endoscopy + CT Multi-modal System for Radiation Therapy Treatment Planning |
Link |
Link |
| C. Coolens, H. Keller |
Calibration Phantom/Software for Dynamic Contrast MR/CT Imaging |
Link |
Link |
| L. White, M. Sussman, G. Andreisek, N. Young |
Synthetic Echo-Time Viewing Technique and Software for MR Imaging |
Link |
Link |
| D. Letourneau, M. Sharpe, D. Jaffray |
Automated IMRT Beam Model Commissioning Platform for Treatment Planning Systems |
Link |
Link |
| B. Wilson, A. Kim |
In-Vivo Fiberoptic Probe for Intra-operative Fluorescence Quantification in Tissue |
Link |
Link |
| Y-B Cho, M. Islam, D. Jaffray, M. van Prooijen, A. Zhang |
Head Frame Collision Avoidance and Virtual Planning Software for Gamma Knife® |
Link |
Link |
| B. Norrlinger, M. Islam, R. Heaton |
Web-Based Barometer and Thermometers for Radiation Therapy QA |
Link |
Link |
| B. Norrlinger, T. Hammer, G. Parsons, D. Jaffray, M. Islam |
LINAC Monitoring System |
Link |
Link |
| G. Disney, D. Jaffray, T. Michaelson, S. Rose, M. Sharpe |
Web-Publishing - Paperless Radiation Treatment Plan Review and Approval |
Link |
Link |
| T. Michaelson, B. Guibord, D. Payne |
E-Booking -Order Entry and Work-Flow Software for Radiation Oncology Clinics |
Link |
Link |
| G. Disney, M. Sharpe, P. Homer, I. Svistoun |
Lightweight Web-Based DICOM RT Viewer |
Link |
Link |
| R. DaCosta; B. Wilson; K. Zhang |
Hand-held Digital Imaging Platform for Wound-Care and Other Applications |
Link |
Link |
| M. Sherar; C. McCann |
Coil-RFA: Novel Radio-Frequency Ablation Technology for Treatment of Solid Tumors |
Link |
Link |
| M.Islam; et al |
Tandem Imaging System: Real-time Imaging During Radiation Therapy Treatment |
Link |
Link |
| M. Sussman; T. Roberts |
Motion Compensation in MRI: Navigator Echo |
Link |
Link |
| N. Munce; V. Yang; A. Thind; B. Courtney |
A Forward-viewing Intravascular Imaging and Guided Therapeutic Intervention |
Link |
Link |
| J. Barfett; T. Krings; D. Mikulis |
3D CT Images Reconstructed from 4D CT Data |
Link |
Link |
| D. Jaffray; J. Hoisak; M. Kaus; T. Purdie |
4D CT capability for 3D CT scanners |
Link |
Link |
| A. Rink; D. Jaffray; A. Vitkin |
Real-Time Radiochromic Dosimeter |
Link |
Link |
| S. Burch; B. Wilson; S. Bisland |
Bone Cancer PDT Treatment Device
|
Link |
Link |
| A. Bogaards; B. Wilson |
Fluorescence Quantification for Image Guided Surgery |
Link |
Link |
| Y-B. Cho; et al |
Stereotactic Radiosurgery Quality Assurance Phantom |
Link |
Link |
| J. Cafazzo; et al |
Bluetooth/USB Adapter for Medical Devices |
Link |
Link |
| J. Cafazzo;et al |
Mobile Phone Disease Management |
Link |
Link |
[Contact]
Cell Lines
UHN
PI |
Cell Line |
Publication
Link |
| Abhijit Guha |
PTEN deficient ES cells |
|
| Abhijit Guha |
Tetracycline inducible human glioma cell lines |
1 - Link
2 - Link
3 - Link |
| Andres Lozano |
SH-SY5Y Stable Cell lines |
Link |
| Jiang Liu |
H460 SM lung cancer cell line |
|
| Shuzo Sugita |
Munc18-1 knockdown PC12 cells |
Link |
| Shuzo Sugita |
Munc18-1 and -2 double knockdown PC12 cells |
Link |
| Shuzo Sugita |
CAPS1 knockdown PC12 cells |
Link |
| Armand Keating |
EM2eGFPluc |
|
[Contact] [Biological MTA - non-profit only]
Antibodies
| UHN Inventor(s) |
Antibody |
Exclusive/Non-exclusive License |
Clonality |
Publication
Link |
| H. Okada |
antibodies for mouse Bat3 (rabbit) |
non-exclusive |
Polyclonal |
Link |
| C. Virtanen; M. Takahashi; J. Paris |
antibodies for mouse DAPR (rabbit) |
non-exclusive |
Polyclonal |
Link |
[Contact] [Antibody License Agreement]
Diagnostics
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| D. Jaffray; et al |
Multi-Modal Imaging Contrast Agent |
Link |
Link |
| M-S. Tsao; et al |
Genomic Markers for Malignant Progression in Pulmonary Adenocarcinoma with Bronchioloalveolar Features |
Link |
Link |
| S. Keshavjee; T. Waddell; M.Y. Liu |
Genomic Signature for Lung Transplant Viability |
Link |
Link |
| D. Kelvin; M.J. Cameron; D. Persad |
Early SARS Infection, Detection, and Prognosis |
Link |
Link |
| L. Lilge; B. Wilson; M. Simick |
Optical Breast Spectroscopy for Cancer Risk Assessment |
Link |
Link |
| K. Kain; W. Liles; F. Lovegrove |
Diagnostic and Prognostic Markers of Severe and Cerebral Malaria |
Link |
Link |
| P. Liu; S. Arab; L. Zhang |
Peripheral Blood Marker that Distinguishes
Systolic and Diastolic Heart Failure |
Link |
Link |
| L. Penn; P. Boutros; J. Clendening |
Molecular Signatures for Statin Sensitivity
in Multiple Myeloma Patients |
Link |
Link |
[Contact]
Research Tools
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| J. Gariepy; A. McCluskey; G. Poon |
Rapid, High-Purity, Low-Cost Purification System for
Recombinant Proteins |
Link |
Link |
| G. Privé |
Protein Stabilizing Detergent |
Link |
Link |
| N. Chirgadze; J. Miller; R.Lam, K. Johns |
Crystallization Device for High-Throughput Visual
Inspection and X-Ray Diffraction Analysis |
Link |
Link |
[Contact]
Software
| UHN Copyright |
Software Name |
Field of Use |
Link/ Description |
| 2004 |
eCancerCare: Streamlining data collection for effective disease management and research |
Synoptic reporting, chronic disease patient managment tool, cancer care |
Link |
| 2005 |
SIMS Whiteboard |
Patient, physician, nurse tracking system |
Link |
| 2005 |
NAViGaTOR and I2D: Gene and Protein Integration Database and Graphing Software |
Network visualization and analysis of Protein-Protein interactions |
Link |
| 2005 |
Media Tracker Software |
Public Relations, Communications |
Link |
| 2005 |
Tuberculosis Management Database |
Tuberculosis/Infectious Disease Clinics |
Link |
| 2005 |
EMITT: Electronic Medication Information Transfer Tool |
Medication Reconciliation |
Link |
2008 |
Patient Relations Training DVD |
Patient Relations, Communications |
Link |
| 2005 |
The Lupus Health Passport |
Patient Relations, Communications |
Link |
[Contact]
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