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Featured Technologies
Available for Licensing / Transfer
Below we describe some of the technologies that have been
developed by UHN investigators. These inventions have been assessed by our office and screened for
development potential and marketability. View: Therapeutics, Delivery Strategies, Medical Devices, Cell Lines, Antibodies, Research Tools, Software or Diagnostics.
Therapeutics
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| J. Dick; E. Lechman; K. Hope |
MicroRNA-126 for Enhancing Stem Cell Engraftment and Monitoring the Treatment of Acute Myeloid Leukemia |
Link |
Link |
| E. Ito; F-F. Liu |
Enhancing Sensitivity to Radiotherapy and Chemotherapy of Head and Neck Cancer |
Link |
Link |
| J. Medin; C. Paige |
IL-12 Immunotherapy for the Treatment of Cancer |
Link |
Link |
| J. Medin; Andrea McCart |
Immunotherapy for Cancer via Lentiviral Mediated
Cancer Antigen Administration |
Link |
Link |
| A. Schimmer; et al |
Ivermectin in Combination with Cytarabine and/or Daunorubicin for Treatment of Lymphoid Malignancies |
Link |
Link |
| J. Dick; et al |
Leukemia and Hematopoietic Stem Cell Signatures
for Predicting Survival of Patients Having Acute Myeloid Leukemia |
Link |
Link |
| L. Penn; A. Schimmer; A. Pandyra |
Treating Cancer with Statins and Dipyridamole |
Link |
Link |
| M. Fehlings; S. Robins |
The Therapeutic Use of IgG as a Neuroprotective Agent |
Link |
Link |
| M. Erwin; R. Inman; M. Fehlings |
Notochordal Cells for Treatment of Degenerative Disk Diseases |
Link |
Link |
| I. Crandall; W. Szarek |
Novel Antibiotic Agents |
Link |
Link |
| L. Kotra; K. Kain; E. Pai |
ODCase Inhibitors as Novel Anti-Malarial Drugs |
Link |
Link |
| K. Kain; L. Serghides |
Treatment for Severe and Cerebral Malaria |
Link |
Link |
| I. Crandall; W. Szarek |
Small Molecule Malaria Invasion Inhibitors |
Link |
Link |
[Contact]
Delivery Strategies
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| J. Chen; Z. Zhang; I. Corbin; G Zheng |
Multifunctional Nanoparticles for Targeted Drug Delivery of Cancer Therapeutics |
Link |
Link |
| J. Gariepy |
Loligomers: Targeted Intracellular Drug Delivery Vehicles |
Link |
Link |
[Contact]
Medical Devices
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| D. Galbraith, R. Heaton, M. Islam, D. Jaffray, B. Norrlinger, J. Smale |
Integrated Quality Monitor for Independent RT Verification |
Link |
Link |
| B. Wilson, A. Kim |
Sub-Surface Fluorescence Topography for Depth-resolved Fluorescence of Buried Pathologies |
Link |
Link |
| D. Jaffray, J. Siewerdsen, R. Weersink, A. Hope, A. Kashigar, M. Daly, J. Eubank, J. Cho |
Endoscopy + CT Multi-modal System for Radiation Therapy Treatment Planning |
Link |
Link |
| C. Coolens, H. Keller |
Calibration Phantom/Software for Dynamic Contrast MR/CT Imaging |
Link |
Link |
| L. White, M. Sussman, G. Andreisek, N. Young |
Synthetic Echo-Time Viewing Technique and Software for MR Imaging |
Link |
Link |
| D. Letourneau, M. Sharpe, D. Jaffray |
Automated IMRT Beam Model Commissioning Platform for Treatment Planning Systems |
Link |
Link |
| B. Wilson, A. Kim |
In-Vivo Fiberoptic Probe for Intra-operative Fluorescence Quantification in Tissue |
Link |
Link |
| Y-B Cho, M. Islam, D. Jaffray, M. van Prooijen, A. Zhang |
Head Frame Collision Avoidance and Virtual Planning Software for Gamma Knife® |
Link |
Link |
| B. Norrlinger, M. Islam, R. Heaton |
Web-Based Barometer and Thermometers for Radiation Therapy QA |
Link |
Link |
| B. Norrlinger, T. Hammer, G. Parsons, D. Jaffray, M. Islam |
LINAC Monitoring System |
Link |
Link |
| G. Disney, D. Jaffray, T. Michaelson, S. Rose, M. Sharpe |
Web-Publishing - Paperless Radiation Treatment Plan Review and Approval |
Link |
Link |
| T. Michaelson, B. Guibord, D. Payne |
E-Booking -Order Entry and Work-Flow Software for Radiation Oncology Clinics |
Link |
Link |
| G. Disney, M. Sharpe, P. Homer, I. Svistoun |
Lightweight Web-Based DICOM RT Viewer |
Link |
Link |
| R. DaCosta; B. Wilson; K. Zhang |
Hand-held Digital Imaging Platform for Wound-Care and Other Applications |
Link |
Link |
| M. Sherar; C. McCann |
Coil-RFA: Novel Radio-Frequency Ablation Technology for Treatment of Solid Tumors |
Link |
Link |
| M.Islam; et al |
Tandem Imaging System: Real-time Imaging During Radiation Therapy Treatment |
Link |
Link |
| M. Sussman; T. Roberts |
Motion Compensation in MRI: Navigator Echo |
Link |
Link |
| N. Munce; V. Yang; A. Thind; B. Courtney |
A Forward-viewing Intravascular Imaging and Guided Therapeutic Intervention |
Link |
Link |
| J. Barfett; T. Krings; D. Mikulis |
3D CT Images Reconstructed from 4D CT Data |
Link |
Link |
| D. Jaffray; J. Hoisak; M. Kaus; T. Purdie |
4D CT capability for 3D CT scanners |
Link |
Link |
| A. Rink; D. Jaffray; A. Vitkin |
Real-Time Radiochromic Dosimeter |
Link |
Link |
| S. Burch; B. Wilson; S. Bisland |
Bone Cancer PDT Treatment Device
|
Link |
Link |
| A. Bogaards; B. Wilson |
Fluorescence Quantification for Image Guided Surgery |
Link |
Link |
| Y-B. Cho; et al |
Stereotactic Radiosurgery Quality Assurance Phantom |
Link |
Link |
| J. Cafazzo; et al |
Bluetooth/USB Adapter for Medical Devices |
Link |
Link |
| J. Cafazzo;et al |
Mobile Phone Disease Management |
Link |
Link |
[Contact]
Cell Lines
UHN
PI |
Cell Line |
Publication
Link |
| Abhijit Guha |
PTEN deficient ES cells |
|
| Abhijit Guha |
Tetracycline inducible human glioma cell lines |
1 - Link
2 - Link
3 - Link |
| Allen Volchuk |
Insulinoma cell lines |
Link |
| Andres Lozano |
SH-SY5Y Stable Cell lines |
Link |
| Mark Minden |
Acute Myeloid Leukemia (AML) cell lines – AML-5 |
|
| Mark Minden |
Well characterized diffuse large B-cell lymphoma (DLBCL) cell lines available for non-exclusive license. Cells available:OCI-Ly1, OCI-Ly2, OCI-Ly3, OCI-Ly4, OCI-Ly6, OCI-Ly7, OCI-Ly10, OCI-Ly18, OCI-Ly19 |
|
| Shuzo Sugita |
Munc18-1 knockdown PC12 cells |
Link |
| Shuzo Sugita |
Munc18-1 and -2 double knockdown PC12 cells |
Link |
| Shuzo Sugita |
CAPS1 knockdown PC12 cells |
Link |
| Armand Keating |
EM2eGFPluc |
|
[Contact]
Antibodies
| UHN Inventor(s) |
Antibody |
Exclusive/Non-exclusive License |
Clonality |
Publication
Link |
| H. Okada |
antibodies for mouse Bat3 (rabbit) |
non-exclusive |
Polyclonal |
Link |
| C. Virtanen; M. Takahashi; J. Paris |
antibodies for mouse DAPR (rabbit) |
non-exclusive |
Polyclonal |
Link |
| M. Liu |
antibodies for XB130 |
non-exclusive |
Monoclonal |
Link |
[Contact] [Antibody License Agreement]
Diagnostics
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| D. Jaffray; et al |
Multi-Modal Imaging Contrast Agent |
Link |
Link |
| M-S. Tsao; et al |
Genomic Markers for Malignant Progression in Pulmonary Adenocarcinoma with Bronchioloalveolar Features |
Link |
Link |
| S. Keshavjee; T. Waddell; M.Y. Liu |
Genomic Signature for Lung Transplant Viability |
Link |
Link |
| D. Kelvin; M.J. Cameron; D. Persad |
Early SARS Infection, Detection, and Prognosis |
Link |
Link |
| L. Lilge; B. Wilson; M. Simick |
Optical Breast Spectroscopy for Cancer Risk Assessment |
Link |
Link |
| K. Kain; W. Liles; F. Lovegrove |
Diagnostic and Prognostic Markers of Severe and Cerebral Malaria |
Link |
Link |
| I. Jurisica, S. Kamel-Reid, P. Reis |
Robust 4-gene signature to predict OSCC recurrence |
Link |
Link |
[Contact]
Research Tools
UHN
Inventor(s) |
Technology Description |
Publication
Link |
One Page
Overview |
| S. Berger |
Novel Method for Increasing Antibody Production |
Link |
Link |
| G. Privé |
Protein Stabilizing Detergent |
Link |
Link |
[Contact]
Software
| UHN Copyright |
Software Name |
Field of Use |
Link/ Description |
| 2004 |
eCancerCare: Streamlining data collection for effective disease management and research |
Synoptic reporting, chronic disease patient managment tool, cancer care |
Link |
| 2005 |
SIMS Whiteboard |
Patient, physician, nurse tracking system |
Link |
| 2005 |
NAViGaTOR and I2D: Gene and Protein Integration Database and Graphing Software |
Network visualization and analysis of Protein-Protein interactions |
Link |
| 2005 |
Media Tracker Software |
Public Relations, Communications |
Link |
| 2005 |
Tuberculosis Management Database |
Tuberculosis/Infectious Disease Clinics |
Link |
[Contact]
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