Drug Development Program (DDP) Biomarker Laboratory

Formerly AMPL, DDP has core technologies in cytomics, genomics and pharmacokinetics for the molecular profiling of tumour samples in clinical and preclinical studies.
Overview
  • Added to our competencies in cytomics/genomics/pharmacokinetics, we offer specialized consultation biomarker development within the realm of clinical study and research program protocols
  • We have processed specimens for clinical trials conducted by the Princess Margaret Cancer Centre Drug Development Program (DDP), the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG) and industry sponsored projects

The Co-Directors of the facility are:
Unique Capacities
We provide a continuum of quality control procedures starting from specimen collection to preparation & analysis.
Services

Cytomics

  • Tissue preparation, tissue microarray construction, immunolabelling
  • ELISA
  • R&D flow cytometry, single-cell signal activation analysis

Genomics

  •  Gene mutations & single nucleotide polymorphisms (sequencing, real-time qPCR)

Pharmacokinetics

  • HPLC-MS-MS analysis of blood and tissue samples
Using the Facility
  • Accessible to internal, external-academic and external customers
  • Research Ethics Board (REB) documents must accompany projects using human specimens and meet UHN REB standards

Usage Arrangements
  • Fee for service – customizable work process
  • Consultation for study design
  • Method development & optimization
  • Sample collection, preparation & analysis
Contacts
Dr. Nhu-An Pham
Manager
 
Promotions

New offers for Princess Margaret Researchers (Limited time)

•Free IHC optimization (antibodies provided by PI).
•Free IHC staining for preliminary results (<5 slides per PI).
•Discounts based on slide volume.

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Formerly AMPL, DDP has core technologies in cytomics, genomics and pharmacokinetics for the molecular profiling of tumour samples in clinical and preclinical studies.
Overview
  • Added to our competencies in cytomics/genomics/pharmacokinetics, we offer specialized consultation biomarker development within the realm of clinical study and research program protocols
  • We have processed specimens for clinical trials conducted by the Princess Margaret Cancer Centre Drug Development Program (DDP), the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG) and industry sponsored projects

The Co-Directors of the facility are:
Unique Capacities
We provide a continuum of quality control procedures starting from specimen collection to preparation & analysis.
Services

Cytomics

  • Tissue preparation, tissue microarray construction, immunolabelling
  • ELISA
  • R&D flow cytometry, single-cell signal activation analysis

Genomics

  •  Gene mutations & single nucleotide polymorphisms (sequencing, real-time qPCR)

Pharmacokinetics

  • HPLC-MS-MS analysis of blood and tissue samples
Using the Facility
  • Accessible to internal, external-academic and external customers
  • Research Ethics Board (REB) documents must accompany projects using human specimens and meet UHN REB standards

Usage Arrangements
  • Fee for service – customizable work process
  • Consultation for study design
  • Method development & optimization
  • Sample collection, preparation & analysis
Contacts
Dr. Nhu-An Pham
Manager
 
Promotions

New offers for Princess Margaret Researchers (Limited time)

•Free IHC optimization (antibodies provided by PI).
•Free IHC staining for preliminary results (<5 slides per PI).
•Discounts based on slide volume.