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Donald R Branch, PhD

Affiliate Scientist
Division of Advanced Diagnostics - Infection & Immunity
Toronto General Research Institute (TGRI)

Keywords: signal transduction, cancer, HIV pathogenesis, Src kinase, transfusion medicine, SHP-1 phosphatase 

Research Interests
Dr. Branch's current interests can be broken down into 4 main areas:
  • Signaling involving c-Src

  • Signaling in HIV/AIDS pathogenesis and disease resistance

  • Signaling abnormalities in the immune response following Rh immune prophylaxis and other IVIg prophylatic therapies

  • Mechanism of IVIG effect in autoimmune inflammatory diseases


More specifically, Dr. Branch is now working on the following:
  • The function of pp60c-src and Pyk2 in HIV infection

  • The role of signaling through the VPAC family of neuroendocrine receptors on HIV/AIDS infection and resistance to infection

  • Drug discovery for small molecular weight molecules that block HIV fusion

  • Identification of novel treatment modalities for HIV/AIDS

  • The signaling pathways used by HIV for its early stages of its life cycle

  • The mechanism of IVIG treatment for autoimmune inflammatory diseases

  • Drug discovery for small molecular weight molecules that inhibit phagocytosis

  • The mechanism of anti-D immune prophylaxis and treatment of ITP

Pubmed Publications
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  Donald  R Branch
Mailing Address
Primary Office
Toronto General Hospital
Canadian Blood Services
3rd Floor Rm. 342
67 College St
Toronto, Ontario
Canada M5G 2M1

 
Email

Phone Numbers
416-313-4458(Primary)

 
Staff and Trainees
Darinka Sakac
Danila Leontyev
Yulia Katsman
Stephen McCarthy
Evgenia Bloch
Carlyn Figueiredo
Iain Scovell
Anton Neschadim

   
 
 
 
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