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Donald R Branch, PhD
Affiliate Scientist, Toronto General Research Institute (TGRI)
Keywords: signal transduction, cancer, HIV pathogenesis, Src kinase, transfusion medicine, SHP-1 phosphatase 

Research Interests
Dr. Branch's current interests can be broken down into 4 main areas:
  • Signaling involving c-Src

  • Signaling in HIV/AIDS pathogenesis and disease resistance

  • Studies of SHP-1 tyrosine phosphatase in malignancies

  • Mechanism of IVIG effect in autoimmune inflammatory diseases

More specifically, Dr. Branch is now working on the following:
  • The function of pp60c-src and Pyk2 in HIV infection

  • The role of signaling through the VPAC family of neuroendocrine receptors on HIV/AIDS infection and resistance to infection

  • Drug discovery for small molecular weight molecules that block HIV fusion

  • Identification of novel treatment modalities for HIV/AIDS

  • The signaling pathways used by HIV for its early stages of its life cycle

  • The mechanism of IVIG treatment for autoimmune inflammatory diseases

  • Drug discovery for small molecular weight molecules that inhibit phagocytosis

  • The mechanism of anti-D immune prophylaxis and treatment of ITP

  • Drug discovery for alternatives to IVIG

Pubmed Publications
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  Donald  R Branch
Mailing Address
Primary Office
Toronto General Hospital
Canadian Blood Services
3rd Floor Room 342
67 College St.
Toronto, Ontario
Canada M5G 2M1


Phone Numbers

Staff and Trainees
Stephen McCarthy
Anton Neschadim
Darinka Sakac
Yulia Katsman
Carlyn Figueiredo
Iain Scovell
Danila Leontyev

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