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Donald R Branch, PhD

Affiliate Scientist
Division of Cellular & Molecular Biology
Toronto General Research Institute (TGRI)

Keywords: signal transduction, cancer, SHP-1 phosphatase, Src kinase, transfusion medicine, HIV pathogenesis 

Research Interests
Dr. Branch's current interests can be broken down into 4 main areas:
  • Signaling involving c-Src

  • Signaling in HIV/AIDS pathogenesis and disease resistance

  • Signaling abnormalities in the immune response following Rh immune prophylaxis and other IVIg prophylatic therapies

  • Mechanism of IVIG effect in autoimmune inflammatory diseases


More specifically, Dr. Branch is now working on the following:

  • The function of pp60c-src in hematopoietic cells and HIV infection

  • The role of signaling through the VPAC family of neuroendocrine receptors on HIV/AIDS infection and resistance to infection

  • The role of the glycolipid, Gb3, on HIV/AIDS pathogenesis by specific signaling mechanisms or by provision of lipid rafts for signaling pathways affecting HIV pathogenesis

  • Identification of novel treatments modalities for HIV/AIDS
  • The signaling pathways used by HIV for its entry and integration

  • The mechanism of IVIG treatment for autoimmune inflammatory diseases

  • The mechanism of anti-D immune prophylaxis and treatment of ITP

Pubmed Publications
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  Donald  R Branch
Mailing Address
Primary Office
Toronto General Hospital
Canadian Blood Services
3rd Floor Rm. 342
67 College St
Toronto, Ontario
Canada M5G 2M1

 
Email

Phone Numbers
416-313-4458(Primary)

 
Staff and Trainees
Darinka Sakac  
Yulia Katsman  
Amanda Harrison  
Danila Leontyev  
Stephen McCarthy  
Minji Kim  

   
 
 
 
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