Heart failure is the leading cause of morbidity and mortality in North America. Current therapies focus on the reduction of workload to the heart. As such they may, at best, reduce the progression of cardiac functional loss, but they fail to regenerate the damaged heart. Using genetic mouse models, as well as state-of-the-art imaging techniques, we therefore try to identify molecular pathways -- the manipulation of which could result in reversing the pathophysiological adaptation of the diseased heart. This will result in much improved therapeutical concepts for heart failure.


Additional Appointments

• Robert McEwen Chair in Cardiac Regenerative Medicine
• Full Staff Member in Interventional Cardiology at Toronto General Hospital
• Associate Professor in the Department of Medicine at the University of Toronto