The Kislinger Laboratory is located at the Princess Margaret Cancer Research Tower of the Princess Margaret Cancer Centre, the largest oncology treatment and research facility in Canada. The major goal of our lab is to apply proteomics technologies to cancer and cardiovascular research. Our research interests include technology development, using the latest generation of mass spectrometry instrumentation, basic cell biology and translational cancer research.
Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.
J Proteome Res. 2011 Jan 7;10(1):161-74
System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.
Clin Cancer Res. 2010 Sep 15;16(18):4572-82
Endoplasmic reticulum protein targeting of phospholamban: a common role for an N-terminal di-arginine motif in ER retention?
PLoS One. 2010;5(7):e11496
PLoS One. 2010;5(5):e10854
Proteome analysis of mouse model systems: A tool to model human disease and for the investigation of tissue-specific biology.
J Proteomics. 2010 Oct 10;73(11):2205-18
PLoS One. 2010;5(3):e9797
J Proteome Res. 2010 May 7;9(5):2109-16
Expert Rev Proteomics. 2010 Feb;7(1):141-54
Method for the affinity purification of covalently linked peptides following cyanogen bromide cleavage of proteins.
Anal Chem. 2009 Dec 15;81(24):9885-95
Nat Struct Mol Biol. 2009 Dec;16(12):1286-93
Senior Scientist, Princess Margaret Cancer Centre